The Lancet Global Health: People with AIDS are six times more likely to develop cervical cancer

Cervical cancer is one of the common gynecological malignancies, and the incidence rate is second among female malignant tumors in China.
2015 China Cancer Report, there are about 130,000 new cases of cervical cancer in China each year.
Thankfully, cervical cancer is currently the only cancer with a clear cause, and the number one risk factor is the human papillomavirus (HPV), and AIDS (HIV) enhances the carcinogenic effects induced by the human papillomavirus (HPV).
, the effects of population-based HIV on cervical cancer have not yet been quantified.
study, published today in The Lancet Global Health, analyzed the risk of cervical cancer in women infected with HIV and estimated the global burden of HIV-related cervical cancer.
in this study, researchers from five databases, including PubMed, Embase, Global Health, Web of Science and Global Index Medicus, conducted systematic literature searches that eventually included 24 studies from 1981 to 2016 involving 236,127 HIV-infected women from four continents (Africa, Asia, Europe and North America).
researchers estimated the combined risk of cervical cancer in these women.
By combining the risk ratio (RR) and estimates of HIV incidence in unAIDS-specific countries with GLOBOCAN 2018 cervical cancer estimates, the proportion of women infected with HIV in cervical cancer, as well as the percentage of hiv-related cervical cancer attribution and age-standardized morbidity (ASIR).
showed an increased risk of cervical cancer in women infected with HIV.
were six times more likely to develop cervical cancer than women who were not infected with HIV.
, there were 33,000 new cases of cervical cancer in 2018, of which 5.8% were diagnosed with HIV and 4.9% were due to HIV infection.
most affected areas are southern Africa and eastern Africa.
in southern Africa, 63.8 per cent of women with cervical cancer are HIV-infected, and in eastern Africa, 27.4 per cent of women with cervical cancer are HIV-infected.
ASIR, which is caused by HIV, is more than 20% in six countries, both in southern and eastern Africa.
the world's top 50 countries, the proportion of the population with cervical cancer and HIV in 2018 overall, hiv-infected women have a significant increased risk of cervical cancer.
it is particularly important to vaccinate women living with HIV against human papillomavirus and cervical cancer screening, particularly in countries and regions in southern and eastern Africa.
of course, HIV-infected women not only increase the risk of cervical cancer, but also increase the risk of non-Hodgkin's lymphoma, Kaposi sarcoma and other tumors.
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