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Selegiline Hydrochloride is a pharmaceutical compound that is commonly used in the treatment of Parkinson's disease.
It is a selective monoamine oxidase inhibitor (MAOI), which means that it selectively blocks the activity of the enzyme monoamine oxidase, which is responsible for breaking down certain neurotransmitters in the brain.
Selegiline Hydrochloride is a prescription medication that should only be taken under the guidance of a healthcare professional.
The chemical structure of Selegiline Hydrochloride is similar to that of other MAOIs, such as phenelzine and tranylcypromine.
It has a molecular weight of 365.
82 g/mol and contains a phenethylamine group, which is responsible for its MAOI activity.
Selegiline Hydrochloride is a white to yellowish crystalline solid that is practically insoluble in water but soluble in alcohol.
Selegiline Hydrochloride is primarily metabolized by the liver enzyme CYP2D6, which converts it into several metabolites, including N-desmethylselegiline and N,N-dimethylselegiline.
These metabolites also have MAOI activity and can contribute to the overall effect of Selegiline Hydrochloride.
The metabolism of Selegiline Hydrochloride can be affected by a number of factors, including genetic differences in CYP2D6 activity, the use of other medications that affect CYP2D6, and the presence of certain foods that can inhibit CYP2D6.
Selegiline Hydrochloride is usually given orally in tablet form, with the recommended dose ranging from 1.
25 mg to 10 mg per day, depending on the specific condition being treated and the patient's response to the medication.
The tablets should be swallowed whole, without crushing or chewing, and should be taken with food to help prevent nausea.
It is important to follow the dosage instructions provided by your healthcare professional carefully, as high doses of Selegiline Hydrochloride can lead to serious side effects.
Selegiline Hydrochloride is contraindicated in certain patients, such as those with a history of hypertensive crisis or critical illness, as it can cause a dangerous increase in blood pressure.
It should also not be used in combination with certain other medications, such as decongestants or amphetamines, as this can lead to serious side effects.
Selegiline Hydrochloride can cause a number of side effects, including nausea, dizziness, fatigue, headache, and insomnia.
These side effects are generally mild and may improve with time, but if they become severe or are accompanied by other symptoms, such as fever, chills, or difficulty breathing, it is important to seek medical attention immediately.
Selegiline Hydrochloride can also interact with other medications, including over-the-counter drugs, herbal supplements, and alcohol, which can increase the risk of side effects or reduce the effectiveness of the medication.
Selegiline Hydrochloride should be stored at room temperature, away from light and moisture, and should not be stored in the bathroom or near a sink.
It is important to keep the medication in its original container and to use a child-resistant closure to prevent accidental ingestion or contamination.
In conclusion, Selegiline Hydrochloride is a commonly used pharmaceutical compound that is primarily used to treat Parkinson's disease.
It is a selective monoamine oxidase inhibitor that blocks the activity of the enzyme monoamine oxidase, which is responsible for breaking down