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Nivolumab is a monoclonal antibody drug that is commonly used in the treatment of cancer.
It is manufactured by the pharmaceutical company Bristol-Myers Squibb and was first approved by the U.
S.
Food and Drug Administration in 2014 for the treatment of melanoma.
Since then, it has been approved for the treatment of a number of other cancers as well, including non-small cell lung cancer, renal cell carcinoma, and Hodgkin's lymphoma.
Nivolumab works by blocking a protein called programmed death-1 (PD-1), which is found on the surface of immune cells.
By blocking PD-1, nivolumab helps to activate the immune system and encourage it to attack cancer cells.
This is a relatively new approach to cancer treatment, known as immuno-oncology, which seeks to harness the power of the immune system to fight cancer.
The instructions for the use of nivolumab vary depending on the specific cancer being treated and the patient's individual medical history.
In general, nivolumab is given intravenously by a healthcare professional in a medical setting.
The dosage and frequency of the treatment will also vary depending on the specific treatment regimen.
Nivolumab is typically administered in combination with other cancer treatments, such as chemotherapy or radiation therapy.
It is also sometimes used as a standalone treatment for patients who have not responded well to other therapies.
One of the main benefits of nivolumab is that it has shown effectiveness in treating a variety of different types of cancer, including some that have been resistant to other treatments.
It is also relatively well-tolerated by patients, with fewer side effects compared to some other cancer treatments.
However, as with any cancer treatment, there are potential risks and side effects associated with nivolumab.
These can include fatigue, diarrhea, and rash, as well as more serious side effects such as inflammation of the intestines, lung inflammation, and immune-related adverse events.
Patients may also experience increased risk of infections while receiving nivolumab.
Despite these potential risks, nivolumab has shown promising results in clinical trials and has become an important treatment option for many patients with cancer.
It is important for patients to discuss the potential benefits and risks of nivolumab with their healthcare provider and to carefully follow the instructions for its use in order to maximize its effectiveness and minimize the risk of side effects.
In conclusion, nivolumab is a promising new treatment option for patients with cancer, particularly those who have not responded well to other therapies.
Its mechanism of action, as a immuno-oncology drug that blocking PD-1 and activate immune system, is unique among cancer treatments, and its ability to be used in combination with other treatments make it a attractive option for patients and oncologists.
It is important for patients to carefully follow the instructions for the use of nivolumab and to discuss the potential benefits and risks of the treatment with their healthcare provider in order to make informed decisions about their cancer care.