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The Lesinurad is a drug that is used in the treatment of gout, a painful condition that affects the joints.
It is a uric acid lowering drug that is used to reduce the levels of uric acid in the blood, which helps to prevent the formation of urate crystals that cause pain and inflammation in the joints.
The drug is manufactured by German pharmaceutical company, Merck KGaA, and was first approved by the US Food and Drug Administration (FDA) in 2015.
The chemical structure of Lesinurad is unique and is classified as a uric acid reabsorption inhibitor.
It works by inhibiting the absorption of uric acid in the kidneys, which leads to an increase in the excretion of uric acid in the urine.
By reducing the levels of uric acid in the blood, Lesinurad helps to prevent the formation of urate crystals that cause pain and inflammation in the joints.
Lesinurad is primarily used in the treatment of gout, a painful condition that affects the joints.
Gout is caused by a buildup of uric acid in the blood, which leads to the formation of urate crystals in the joints.
The crystals cause pain, inflammation, and swelling in the affected joints, which can be very painful.
Lesinurad is used to reduce the levels of uric acid in the blood, which helps to prevent the formation of urate crystals in the joints.
The drug is usually taken once daily, and the full effect of the drug is typically seen within two to four weeks of starting treatment.
It is usually used in combination with other gout medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and colchicine, to provide maximum relief from symptoms.
Lesinurad is taken orally, and it is usually taken once daily.
The drug is usually taken with food to help improve its absorption.
The dosage of the drug will depend on the individual patient, and it may need to be adjusted based on the patient's response to treatment.
The drug should be taken exactly as prescribed by the healthcare provider.
It is important to note that Lesinurad can interact with certain medications, such as diuretics, aspirin, and cyclosporine.
It is important to consult with a healthcare provider before starting treatment with Lesinurad to ensure that it is safe to use with other medications that are being taken.
Lesinurad has been well-tolerated in clinical trials, and the most common side effects reported include nausea, diarrhea, and headache.
These side effects are usually mild and do not require treatment.
It is important to consult with a healthcare provider if any severe side effects occur.
In conclusion, Lesinurad is a uric acid lowering drug that is used to reduce the levels of uric acid in the blood, which helps to prevent the formation of urate crystals that cause pain and inflammation in the joints.
It is primarily used in the treatment of gout, and it is usually taken in combination with other gout medications to provide maximum relief from symptoms.
The drug is usually well-tolerated, but it can interact with certain medications, and it is important to consult with a healthcare provider before starting treatment with Lesinurad.
