The Instruction of ethyl2-methylquinoline-6-carboxylate

Ethyl 2-methylquinoline-6-carboxylate, also known as EMQ, is a chemical compound that is commonly used in the chemical industry as a building block for the synthesis of various products.
The preparation of EMQ involves several steps, including the reaction of 2-methylquinoline-6-sulphonate with a Grignard reagent, followed by hydrolysis of the resulting intermediate to form the carboxylate.

The synthesis of EMQ has been well-studied in the literature, and there are several methods that have been reported for its preparation.
One common method involves the reaction of 2-methylquinoline-6-sulphonate with a Grignard reagent, such as methyl iodide or ethyl iodide.
This reaction is typically carried out in the presence of a base, such as sodium hydroxide or potassium hydroxide, and is followed by hydrolysis of the resulting intermediate to form the carboxylate.

The use of EMQ as a building block for the synthesis of various products has been reported in the literature.
For example, it has been used in the synthesis of the anti-cancer drug irinotecan, as well as in the synthesis of a variety of other organic compounds.

In addition to its use as a building block for the synthesis of various chemical products, EMQ has also been studied for its potential as a therapeutic agent.
Preliminary studies have shown that EMQ has activity against a variety of cancer cell lines, including colon, prostate, and ovarian cancer cells.
Further research is needed to fully understand the potential therapeutic effects of EMQ and to determine its safety and efficacy as a cancer treatment.

Overall, EMQ is a useful chemical building block in the synthesis of various organic compounds, and it has also shown promising activity against cancer cells in preliminary studies.
Further research is needed to fully understand its potential as a therapeutic agent and to determine its safety and efficacy as a cancer treatment.