The Instruction of ETHYL-4-PHENYL PYRIMIDINE-5-CARBOXYLATE

The chemical industry is a vast and ever-expanding field that involves the production and use of a wide range of chemical compounds.
One of the important chemicals produced in this industry is Ethyl-4-phenyl pyrimidine-5-carboxylate, which has various applications in different sectors.
In this article, we will discuss the production, use, and properties of Ethyl-4-phenyl pyrimidine-5-carboxylate.

What is Ethyl-4-phenyl pyrimidine-5-carboxylate?

Ethyl-4-phenyl pyrimidine-5-carboxylate is an organic compound with the formula C15H14N2O3.
It is also known as 4-phenylpyrimidine-5-carboxylic acid ethyl ester or simply PP5C.
This compound is a type of organic acid that is derived from the reaction of pyridine-5-carboxylic acid and ethyl alcohol.
The chemical structure of PP5C consists of a phenyl group attached to a pyrimidine ring that is further esterified with an ethyl group.

Production of Ethyl-4-phenyl pyrimidine-5-carboxylate

Ethyl-4-phenyl pyrimidine-5-carboxylate is produced industrially through a series of chemical reactions.
The production process typically involves the following steps:

1. Preparation of Pyridine-5-carboxylic acid: Pyridine-5-carboxylic acid is prepared by heating pyridine-5-amine with a strong acid catalyst.
   
2. Esterification with Ethyl Alcohol: Pyridine-5-carboxylic acid is reacted with ethyl alcohol in the presence of an acid catalyst to form Ethyl-4-phenyl pyrimidine-5-carboxylate.
   
3. Purification: The resulting product is purified to remove any impurities that may be present.
   

Uses of Ethyl-4-phenyl pyrimidine-5-carboxylate

Ethyl-4-phenyl pyrimidine-5-carboxylate has a wide range of applications in the chemical industry, including:

1. Pharmaceuticals: PP5C is used as an intermediate in the production of some pharmaceuticals, such as anti-viral drugs and anti-cancer medications.
   
2. Agrochemicals: PP5C is used in the production of some agrochemicals, such as herbicides and insecticides.
   
3. Detergents: PP5C is used as a building block for the production of some detergents and surfactants.
   
4. Fragrances: PP5C is used as a flavoring agent in the production of perfumes and fragrances.
   
5. Cosmetics: PP5C is used in the production of some cosmetics, such as shampoos and soaps.
   

Properties of Ethyl-4-phenyl pyrimidine-5-carboxylate

Ethyl-4-phenyl pyrimidine-5-carboxylate is a colorless liquid that has a characteristic pungent smell.
It is slightly soluble in water but highly soluble in ethanol and other organic solvents.
The compound has a melting point of around 7 degrees Celsius and a boiling point of around 203 degrees Celsius.
It is a weak acid, with a pKa value of around 5.

Health and Safety Considerations

PP5C is a hazardous chemical that can cause skin irritation, respiratory problems, and other health issues if handled without proper precautions.
It is classified as a Category 2 carcinogen by the International Agency for