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6-Chloro-3-methyl-imidazo[1,2-b]pyridazine is a chemical compound that has gained significant attention in the chemical industry due to its unique properties and versatile applications.
This compound is a member of the imidazo[1,2-b]pyridazine family of molecules, which are known for their anticancer, anti-inflammatory, and antiviral activities.
In this article, we will explore the instruction of 6-chloro-3-methyl-imidazo[1,2-b]pyridazine and its applications in the chemical industry.
Background
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine is a synthetic molecule that can be synthesized through several different methods.
One of the most common methods involves the reaction of 2-amino-6-chloro-4-methyl-imidazo[1,2-b]pyridine with 3-methyl-imidazolidine.
This reaction leads to the formation of the target compound in good yield, with the help of basic conditions.
Structure and Properties
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine is a white to off-white crystalline powder with a melting point of about 240-242°C.
The compound displays good thermal stability and is resistant to solvents.
It is soluble in water, methanol, and ethanol, but insoluble in ether and chloroform.
The molecule has a molecular weight of 228.
62 g/mol and possesses a basic nature, with a pKa value of 5.
43.
Applications
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine has several applications in the chemical industry, including use as an intermediate in the synthesis of other chemicals, use as a pharmaceutical agent, and use as a research reagent in various laboratory studies.
Intermediate
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine can be used as an intermediate in the synthesis of other chemicals, such as pharmaceuticals, agrochemicals, and dyes.
For example, it can be converted into 2-[6-(chloromethyl)-3-methyl-1H-imidazo[1,2-b]pyridazin-5-yl]-N-(4-nitrophenyl)acetamide, which is a known anticancer agent.
Pharmaceutical Agent
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine has been studied for its potential as a pharmaceutical agent.
It has been shown to exhibit antiviral and anti-inflammatory activities, which make it a promising candidate for treating viral diseases and inflammation-related disorders.
Research Reagent
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine is also used as a research reagent in various laboratory studies.
For example, it has been used to investigate the anticancer properties of imidazo[1,2-b]pyridazine-based compounds, to study the mechanism of action of anti-inflammatory agents, and to explore the activity of antiviral agents.
Conclusion
6-Chloro-3-methyl-imidazo[1,2-b]pyridazine is a versatile compound with several applications in the chemical industry.
It can be used as an intermediate