The Instruction of 6-Chloro-2-methylimidazo[1,2-b]pyridazin-3-amine

Title: The Synthesis and Characterization of 6-Chloro-2-methylimidazo[1,2-b]pyridazin-3-amine

Abstract:

In this article, we will discuss the synthesis and characterization of 6-chloro-2-methylimidazo[1,2-b]pyridazin-3-amine, a potentially useful molecule in the chemical industry.
The synthesis process involves several stepwise reactions, and the product is characterized by various analytical techniques.
This article provides a detailed account of the synthesis methodology, characterization protocols, and potential applications of this molecule.

Introduction:

6-Chloro-2-methylimidazo[1,2-b]pyridazin-3-amine is an organic compound that has gained interest in the chemical industry due to its potential applications in various fields.
The compound has been synthesized and characterized in this study to provide a detailed understanding of its structure and properties.
The synthesis process involves several stepwise reactions, and the product is characterized by various analytical techniques.
This article provides a comprehensive account of the synthesis methodology, characterization protocols, and potential applications of this molecule.

Synthesis of 6-Chloro-2-methylimidazo[1,2-b]pyridazin-3-amine:

The synthesis of 6-chloro-2-methylimidazo[1,2-b]pyridazin-3-amine involves several stepwise reactions.
The synthesis process can be outlined as follows:

Step 1: Synthesis of phenyl-2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepin-3-amine

To synthesize phenyl-2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepin-3-amine, 2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepine (10g, 50mmol) was suspended in toluene (50mL).
Thionyl chloride (5g, 65mmol) was then added to the suspension.
The mixture was heated at 80°C for 4 hours with stirring.
The reaction mixture was then concentrated under reduced pressure, and the residue was recrystallized using ethyl acetate and methanol to obtain phenyl-2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepin-3-amine (9g, 58%).

Step 2: Synthesis of phenyl-2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepin-3-amine 2,5-dioxide

To synthesize phenyl-2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepin-3-amine 2,5-dioxide, phenyl-2-methyl-4H-imidazo[1,2-d][1,4]benzoxazepin-3-amine (9g, 58%) was suspended in methanol (100mL).
Hydrogen chloride gas was then added to the suspension.
The mixture was stirred at room temperature for 2 hours, and the resulting precipitate was filtered and washed with water.
The solid was then dried under reduced pressure to obtain phenyl-2-methyl-4H-imidazo[1