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6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid, also known as PDP, is a chemical compound that is widely used in the pharmaceutical and chemical industries.
It is a versatile compound that can be synthesized through a variety of methods and can be used in a range of applications.
In this article, we will discuss the instruction of 6-chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid, including its synthesis, properties, and uses in the chemical industry.
Synthesis of 6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid
6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid can be synthesized through a number of methods, including the following:
- From 2,3-dihydro-4-oxo-6-chloro-pyridazine-3-carboxylic acid
To synthesize 6-chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid, one can start with 2,3-dihydro-4-oxo-6-chloro-pyridazine-3-carboxylic acid.
This compound can be synthesized by treating 2,3-dihydro-6-chloro-pyridazine-4-carboxylic acid with a strong acid, such as hydrochloric acid, in the presence of an esterifying agent, such as ethyl acetate. - From 2,3-dihydro-4-oxo-7-chloro-5-phenyl-pyridazine-3-carboxylic acid
Another way to synthesize 6-chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid is to start with 2,3-dihydro-4-oxo-7-chloro-5-phenyl-pyridazine-3-carboxylic acid.
This compound can be synthesized by treating 2,3-dihydro-7-chloro-6-phenyl-pyridazine-4-carboxylic acid with chloroform and an aqueous solution of sodium hydroxide.
Properties of 6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid
6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid is a colorless to white solid that is soluble in water, methanol, and ethanol.
It has a molecular formula of C7H8ClN3O3 and a molecular weight of 191.
02 g/mol.
The compound has a melting point of 230-232°C and a boiling point of 381°C.
It is also hygroscopic and should be stored in a cool, dry place.
6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid is an important intermediate in the synthesis of several pharmaceuticals, including anti-epileptic drugs and anti-tumor agents.
It is also used as a starting material for the synthesis of other organic compounds, such as in the manufacture of dyes and pigments.
Uses of 6-Chloro-2,3-dihydro-3-oxo-4-pyridazinecarboxylic acid
6-Chloro-2,3-