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5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) is an important intermediate in the chemical industry, used in the production of various pharmaceuticals, agrochemicals, and other chemical products.
It is a highly reactive and versatile compound, with a complex chemical structure that is difficult to synthesize.
As a result, the synthesis of 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) is a complex and multi-step process that requires careful control and optimization of the reaction conditions.
One of the most commonly used methods for the synthesis of 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) is the Grignard reaction, in which a Grignard reagent is used to convert a carboxylate ester into an aldehyde.
This reaction involves the treatment of a carboxylate ester with magnesium metal in the presence of an organic solvent, such as ether or hexane.
The Grignard reagent is then used in a subsequent reaction with another compound, such as an alkyl halide, to form the desired aldehyde.
Another method for the synthesis of 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) is the Robson reaction, which involves the use of a metal hydride reagent to convert a carboxylate ester into an aldehyde.
This reaction is typically carried out in the presence of a polar protic solvent, such as water or methanol, and a base, such as sodium hydroxide.
The reaction conditions must be carefully controlled to ensure the formation of the desired product.
The synthesis of 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) can also be accomplished through other methods, such as the Wolff-Kishner reduction or the Kharasch reduction.
These reactions involve the use of various reagents and conditions to reduce a carboxylate ester into an aldehyde.
The choice of method and the specific reaction conditions must be carefully selected based on the desired product and the starting materials available.
Once the 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) has been synthesized, it can be used as a building block for the synthesis of various pharmaceuticals, agrochemicals, and other chemical products.
It has a wide range of applications in the chemical industry due to its ability to react with a variety of other chemicals, such as amines, acids, and alcohols, to form new and useful compounds.
In conclusion, 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) is an important intermediate in the chemical industry, used in the production of various pharmaceuticals, agrochemicals, and other chemical products.
It is a highly reactive and versatile compound, with a complex chemical structure that is difficult to synthesize.
The synthesis of 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) can be accomplished through various methods, such as the Grignard reaction, the Robson reaction, the Wolff-Kishner reduction, and the Kharasch reduction.
The choice of method and the specific reaction conditions must be carefully selected based on the desired product and the starting materials available.
Once the 5-Pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) has been synthesized