The Instruction of 5-CHLOROPYRIDAZIN-3-OL

Title: The Instruction of 5-Chloropyridazine-3-ol in the Chemical Industry: Synthesis, Properties, and Applications

Introduction

5-Chloropyridazine-3-ol is an important organic compound widely used in various industries, including the chemical, pharmaceutical, and agrochemical sectors.
This compound is synthesized by various chemical methods, and its properties and applications make it a valuable commodity in the chemical industry.
In this article, we will discuss the synthesis, properties, and applications of 5-chloropyridazine-3-ol.

Synthesis of 5-Chloropyridazine-3-ol

5-Chloropyridazine-3-ol can be synthesized using various chemical methods, including the nitrosonium salt method, the P2P method, and the Mannich reaction.
The nitrosonium salt method involves the reaction of sodium nitrite and 2-chloropyridine in the presence of a solvent such as ethanol or acetone.
The P2P method, on the other hand, involves the reaction of 2-chloropyridine with hydrogen peroxide in the presence of a Lewis acid catalyst such as aluminum chloride.
The Mannich reaction involves the reaction of 2-chloropyridine with formaldehyde and an aldehyde in the presence of a solvent such as water or ethanol.

Properties of 5-Chloropyridazine-3-ol

5-Chloropyridazine-3-ol is a white or almost white solid with a melting point of 189-191°C and a boiling point of 350-352°C.
It is slightly soluble in water but soluble in most organic solvents.
The compound has a molecular formula of C5H5ClN2OH, and its molecular weight is 161.
01 g/mol.
Its density is 1.
57 g/cm3, and its logarithmic octanol-water partition coefficient is 1.
72.

5-Chloropyridazine-3-ol has various physical and chemical properties that make it suitable for various applications.
It is a moderate lipophilic compound, meaning it is soluble in both water and lipids.
This property makes it suitable for use in pharmaceutical and cosmeceutical preparations, as it can penetrate the skin and lipids in the body.
It also has antimicrobial and antifungal properties, making it suitable for use in various industrial and household applications.

Applications of 5-Chloropyridazine-3-ol

5-Chloropyridazine-3-ol has a wide range of applications in various industries.
In the pharmaceutical industry, it is used as an intermediate for the synthesis of various drugs, including anti-inflammatory, anti-hypertensive, and anti-asthmatic drugs.
It is also used as a raw material for the synthesis of antibiotics, antifungals, and other antimicrobial agents.

In the agrochemical industry, 5-chloropyridazine-3-ol is used as a herbicide, an insecticide, and a fungicide.
It is effective in controlling various plant pathogens, including weeds, insects, and fungi.
It is also used in seed treatment products to protect seeds from fungal infections.

In the industrial sector, 5-chloropyridazine-3-ol is used as a disinfectant, a sanitizer, and a preservative in various applications such as in swimming pools, spas, and hot tubs.
It is also used in household cleaning products, laundry detergents, and fabric softeners.

Conclusion

In conclusion