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In the chemical industry, 4-(N-(3-chloropropyl)sulfamoyl)phenylboronic acid (CAS No: 1217445-72-1) is a commonly used reagent for various chemical reactions.
This acid is also known as 4-CS-PBA.
Due to its unique chemical structure, it has a wide range of applications in the synthesis of organic compounds, polymers, and materials.
The production process of 4-CS-PBA is relatively straightforward and involves several stages, including synthesis, purification, and characterization.
The starting material for the synthesis of 4-CS-PBA is 2-chloromethyl-3-nitrobenzene, which is reacted with sodium dithionite in the presence of a solvent such as water or ethanol to form 2-chloromethyl-1,3-oxazolidin-3-one.
This intermediate is then treated with an excess of ammonia to convert it to 1,3-oxazolidin-3-ol.
The next step in the synthesis of 4-CS-PBA is the reaction of 1,3-oxazolidin-3-ol with phenylboronic acid and sodium hydroxide in the presence of a solvent such as toluene or xylene to form the desired product.
The reaction is typically carried out at a temperature of 100-120°C for several hours.
The product is then purified by recrystallization or chromatography to remove any impurities.
The purified 4-CS-PBA is then characterized by various analytical techniques such as nuclear magnetic resonance spectroscopy (NMR), Fourier transform infrared spectroscopy (FTIR), and high-performance liquid chromatography (HPLC) to determine its chemical structure, purity, and composition.
4-CS-PBA has a wide range of applications in the chemical industry due to its unique chemical structure.
It can be used as a building block for the synthesis of various organic compounds, polymers, and materials.
For example, it can be reacted with an amine or a thiol to form a variety of amides or thioethers, respectively.
It can also be used as a ligand for the synthesis of coordination compounds.
In addition to its use as a building block, 4-CS-PBA can also be used as a catalyst in various chemical reactions.
For example, it can be used as a catalyst for the polymerization of monomers such as styrene or vinyl chloride to form polymers such as polystyrene or polyvinyl chloride.
It can also be used as a catalyst for the hydrolysis of esters or the oxidation of alcohols.
4-CS-PBA can also be used in the synthesis of dyes, pigments, and other colorants.
For example, it can be reacted with a diazo compound such as para-nitroaniline to form a variety of azo dyes.
It can also be used in the synthesis of phthalocyanines, which are used in a variety of applications including inkjet ink, pigments, and optical storage media.
In addition to its applications in the chemical industry, 4-CS-PBA has also been studied for its potential use in biomedical applications.
For example, it has been shown to have antibacterial and antifungal properties, making it a potential candidate for the treatment of bacterial and fungal infections.
It has also been studied for its potential use in the treatment of cancer, although further research is needed to fully understand its therapeutic potential.
In conclusion, 4-(N-(3-chloropropyl)sulfamoyl)phenylboronic acid (CAS No: 1217445-72-