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4-Methyl-8-quinolinamine is a chemical compound that is commonly used in the manufacturing of pharmaceuticals, agrochemicals, and other chemical products.
The use of this compound in chemical industry has increased significantly in recent years due to its unique properties, which make it a versatile building block for the synthesis of various chemicals.
In this article, we will discuss the instruction of 4-methyl-8-quinolinamine, its properties, and its applications in the chemical industry.
Instruction of 4-methyl-8-quinolinamine
4-Methyl-8-quinolinamine is synthesized through a multi-step process that involves the reaction of several starting materials.
The synthesis of this compound typically involves the following steps:
- Conversion of aniline to N-phenyl-4-amino-3-chloropropionamide.
- Condensation of N-phenyl-4-amino-3-chloropropionamide with aniline to form N-[2-(4-aminophenyl)quinolin-4-yl]-N-(2-chloroethyl)amide.
- Deprotection of the amide group to form N-[2-(4-aminophenyl)quinolin-4-yl]amide.
- Condensation of N-[2-(4-aminophenyl)quinolin-4-yl]amide with acrylonitrile to form N-[2-(4-aminophenyl)quinolin-4-yl]-N-(2-chloroethyl)acrylamide.
- Deprotection of the acrylamide group to form N-[2-(4-aminophenyl)quinolin-4-yl]-4-methylaminobutyrate.
- Reduction of N-[2-(4-aminophenyl)quinolin-4-yl]-4-methylaminobutyrate to form 4-methyl-8-quinolinamine.
The above steps provide a general outline of the synthesis of 4-methyl-8-quinolinamine.
However, the specific conditions and reagents used in each step may vary depending on the desired product and the scale of production.
Properties of 4-methyl-8-quinolinamine
4-Methyl-8-quinolinamine is a white to off-white solid that is highly soluble in water and many organic solvents.
This compound has a strong, unpleasant odor that is characteristic of quinoline derivatives.
It is used in various applications due to its unique properties, which include:
- Antimicrobial activity: 4-methyl-8-quinolinamine has been found to have antimicrobial activity against a variety of bacteria, fungi, and viruses.
- Antioxidant activity: The compound has been found to have antioxidant properties and can be used as a preservative in various industrial applications.
- Pharmaceutical applications: 4-methyl-8-quinolinamine is used as an intermediate in the synthesis of various pharmaceuticals, including anti-inflammatory drugs, antibiotics, and anti-tumor agents.
- Agrochemical applications: The compound can be used as a herbicide and as an insecticide in agricultural applications.
Applications of 4-methyl-8-quinolinamine in the chemical industry
4-Methyl-8-quinolinamine is a versatile building block in the synthesis of various chemicals and is used in a wide range of industrial applications.
Some of the most common applications of this compound include:
- Pharmaceuticals: