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4-Chloro-6-methoxyquinoline is an important organic chemical compound that is widely used in the chemical industry.
It is produced through various chemical reactions and is used as an intermediate in the production of various chemicals, drugs, and pesticides.
In this article, we will discuss the instruction of 4-chloro-6-methoxyquinoline and its applications in the chemical industry.
Introduction
4-Chloro-6-methoxyquinoline is a yellow or yellowish-brown crystalline solid that is slightly soluble in water and soluble in organic solvents.
It has a molecular formula of C9H10ClNO and a molecular weight of 196.
16 g/mol.
The compound is a derivative of quinoline and is commonly used as an intermediate in the production of various chemicals, drugs, and pesticides.
Synthesis of 4-Chloro-6-methoxyquinoline
4-Chloro-6-methoxyquinoline can be synthesized through various chemical reactions.
One of the most common methods is the reaction of 4-chloro-2-methylquinoline with methyl iodide in the presence of a base such as sodium hydroxide.
The reaction involves the formation of a Grignard reagent, which is then treated with sodium hydroxide to form the desired product.
The reaction can be represented by the following equation:
4-chloro-2-methylquinoline + 2 MeI → 4-chloro-6-methoxyquinoline + 2 NaOH
Another method for the synthesis of 4-chloro-6-methoxyquinoline involves the reaction of 4-chloro-6-methoxy-2-quinoline with chloroform in the presence of a base such as sodium hydroxide.
The reaction involves the formation of a Grignard reagent, which is then treated with sodium hydroxide to form the desired product.
The reaction can be represented by the following equation:
4-chloro-6-methoxy-2-quinoline + 4 CHCl3 + 2 NaOH → 4-chloro-6-methoxyquinoline + 4 HCl + 2 NaCl
Applications of 4-Chloro-6-methoxyquinoline
4-Chloro-6-methoxyquinoline is used as an intermediate in the production of various chemicals, drugs, and pesticides.
It is a versatile building block for the synthesis of a wide range of compounds and has many applications in the chemical industry.
Some of the common applications of 4-chloro-6-methoxyquinoline are discussed below.
- Pesticides: 4-chloro-6-methoxyquinoline is used in the production of pesticides and insecticides.
It is converted into other compounds that have pesticidal properties and are used to control pests and diseases in crops. - Pharmaceuticals: 4-chloro-6-methoxyquinoline is used in the production of various pharmaceuticals such as anti-inflammatory drugs, painkillers, and antibiotics.
It is converted into other compounds that have therapeutic properties and are used to treat diseases in humans and animals. - Cosmetics: 4-chloro-6-methoxyquinoline is used in the production of cosmetics such as soaps, lotions, and shampoos.
It is used as a fragrance ingredient and provides a unique and distinct odor to the products. - Plastics: 4-chloro-6-methoxyquinoline is used