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4-Bromo-6-methylisoquinoline, commonly referred to as 4-Bromo-MK-212, is a chemical compound that is widely used in the pharmaceutical industry.
This compound is known for its ability to treat a range of medical conditions, including Alzheimer's disease, Parkinson's disease, and depression.
The chemical formula for 4-Bromo-6-methylisoquinoline is C15H16BrClN3O, and it has a molecular weight of 312.
84 g/mol.
The chemical synthesis of 4-Bromo-6-methylisoquinoline is a complex process that involves several steps.
The synthesis of this compound typically begins with the reaction of methyl iodide with 2-bromopyridine in the presence of a strong acid catalyst.
This reaction leads to the formation of 3-bromo-2-methyl-1H-pyrazole, which is then refluxed with sodium hydroxide to yield 4-bromo-2-methyl-1H-pyrazole.
The next step in the synthesis of 4-Bromo-6-methylisoquinoline involves the reaction of 4-bromo-2-methyl-1H-pyrazole with 6-methylisoquinoline in the presence of a strong acid catalyst.
This reaction results in the formation of 4-bromo-6-methylisoquinoline, which can then be purified and isolated using a variety of techniques, such as crystallization or chromatography.
Once synthesized, 4-Bromo-6-methylisoquinoline can be used in a range of pharmaceutical applications.
This compound has been shown to have potential as a treatment for Alzheimer's disease, Parkinson's disease, and depression, among other medical conditions.
One of the most important things to consider when synthesizing 4-Bromo-6-methylisoquinoline is the quality of the starting materials and the reactants used in the synthesis.
It is essential to use high-purity starting materials and to carefully control the reaction conditions in order to ensure that the final product is of the desired purity and quality.
Another important consideration when synthesizing 4-Bromo-6-methylisoquinoline is the safety of the synthesis procedure.
The use of strong acids and reactive reagents can pose a risk to the safety of the synthesist, and it is important to take appropriate precautions to minimize this risk.
In conclusion, the synthesis of 4-Bromo-6-methylisoquinoline is a complex process that requires careful attention to detail and the use of high-quality starting materials and reactants.
The resulting compound has the potential to be used as a treatment for a range of medical conditions, and its synthesis is an important part of the pharmaceutical industry.
It is essential to follow all relevant safety protocols when synthesizing this compound to minimize the risk to the synthesist and to ensure the production of a safe and effective pharmaceutical product.