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4-Amino-6-bromo-2-(trifluoromethyl)quinoline-3-carbonitrile, also known as 2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one, is a compound that is commonly used in the chemical industry.
This compound is a versatile building block that can be used in a variety of synthetic procedures to create a wide range of chemicals and materials.
One of the most common uses for this compound is in the synthesis of pharmaceuticals.
The unique structure of 2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one makes it an ideal starting point for the development of new drugs.
The compound can be easily modified and functionalized to create new compounds with desired properties.
Another common use for 2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one is in the production of agrochemicals.
The compound can be used as a intermediate in the synthesis of herbicides, insecticides, and fungicides.
2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one also finds application in the production of personal care products and cosmetics.
The compound can be used as an ingredient in the formulation of sunscreen products, moisturizers, and other skin care products.
The synthesis of 2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one requires the use of several specialized pieces of equipment and a precise control of reaction conditions.
The synthesis process typically involves several steps, including the preparation of starting materials, the reaction of these materials in the presence of appropriate reagents, and the isolation of the desired product.
One of the most common methods for synthesizing 2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one is through the use of a reaction called a Williamson etherification.
In this process, a halogenated benzene, such as 4-bromo-2-(trifluoromethyl)quinoline-3-carbonitrile, is treated with a diol, such as 1,3-propanediol, in the presence of an acid catalyst, such as sulfuric acid.
The resulting product is then treated with a nitrile, such as acetonitrile, and a metal catalyst, such as copper(II) nitrate, to form the desired product.
Another synthesis method is to use the Reductive Amination reaction where a reactive nitrile such as 2-bromo-4-((6-trifluoromethyl-2-pyridinyl)amino)-5-((E)-2-(dimethylamino)vinyl)-1,3-oxazolidin-3-one is treated with a reducing agent such as Lithium Aluminium Hydroxide and then treated with