-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Introduction
In the chemical industry, there are a wide variety of chemicals that are used for different purposes.
One such chemical is (-)-4-(2-Pyrrolidinyl)pyridine, which is also known as ciprofloxacin.
This antibiotic is used to treat a wide range of bacterial infections, and is commonly prescribed for conditions such as respiratory tract infections, urinary tract infections, and skin infections.
The synthesis of ciprofloxacin involves a number of steps, and the instruction of (-)-4-(2-Pyrrolidinyl)pyridine is a critical part of this process.
In this article, we will take a closer look at the instruction of ciprofloxacin and the role it plays in the production of this important antibiotic.
The biosynthesis of ciprofloxacin
Ciprofloxacin is a synthetic antibiotic that is derived from a naturally occurring compound called ofloxacin.
Ofloxacin is produced by the bacterium Streptomyces plasticireus, and is extracted from the fermentation broth of this bacterium.
The instruction of ciprofloxacin involves a number of steps, including the synthesis of the precursor compound ofloxacin.
The biosynthesis of ofloxacin involves a number of enzymatic steps, including the formation of a precursor compound called 2-pyrrolidinylpyridine.
This compound is synthesized by the bacterium through the action of several enzymes, including the enzyme Pyrrole-2-carboxylate reductase.
This enzyme converts 2-pyrrolidinylpyridine into another compound called 4-hydroxy-2-pyrrolidinylpyridine, which is then converted into ofloxacin through several additional steps.
The synthesis of ofloxacin is a complex process that involves a number of enzymatic steps, and the instruction of (-)-4-(2-Pyrrolidinyl)pyridine is a key step in this process.
In the next section, we will take a closer look at the synthesis of (-)-4-(2-Pyrrolidinyl)pyridine and the role it plays in the production of ofloxacin.
The synthesis of (-)-4-(2-Pyrrolidinyl)pyridine
The synthesis of (-)-4-(2-Pyrrolidinyl)pyridine involves a number of steps, and the instruction of this compound is a critical part of the process.
The synthesis of (-)-4-(2-Pyrrolidinyl)pyridine can be carried out through several different methods, including the classic synthesis developed by R.
B.
Woodward and his coworkers in 1952 and later modified by E.
J.
Corey in 1976.
The synthesis of (-)-4-(2-Pyrrolidinyl)pyridine involves the formation of several intermediate compounds, including 2-pyrrolidinone and 2-aminopyrrole.
These compounds are synthesized through the action of several enzymes, including the enzyme Pyrrolidinone-2,5-dione decarboxylase and the enzyme 2-Aminopyrine synthase.
These enzymes convert the intermediate compounds into (-)-4-(2-Pyrrolidinyl)pyridine, which is then used in the production of ofloxacin.
Conclusion
In conclusion, the instruction of (-)-4-(2-Pyrrolidinyl)pyridine is a critical step in the synthesis of ciprofloxacin, an important antibiotic used to treat a wide range of