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3-Hydroxypiperidin-2-one is a versatile chemical compound that is commonly used in a variety of applications in the chemical industry.
This article will explore the instruction of 3-hydroxypiperidin-2-one, including its chemical structure, synthesis, and uses in the chemical industry.
Chemical Structure of 3-Hydroxypiperidin-2-one
3-Hydroxypiperidin-2-one is a heterocyclic organic compound that contains a six-membered aromatic ring with a nitrogen atom attached to two carbon atoms.
It has a unique molecular structure that consists of a three-carbon aromatic ring fused to a five-carbon aromatic ring, with a hydroxyl group (-OH) attached to the nitrogen atom in the five-carbon ring.
The molecular formula for 3-hydroxypiperidin-2-one is C8H13NO2.
Synthesis of 3-Hydroxypiperidin-2-one
3-Hydroxypiperidin-2-one can be synthesized through several different methods, including the following:
- From 2,2'-diaminobicyclo[2.
2.
1]heptane-2,3-dione: 2,2'-diaminobicyclo[2.
2.
1]heptane-2,3-dione can be treated with potassium hydroxide to form 3-hydroxypiperidin-2-one. - From 4-chloro-2-methylaniline: 4-chloro-2-methylaniline can be treated with sodium hydroxide and then with bromine to form 3-hydroxypiperidin-2-one.
- From 3-bromopiperidine-2,6-dione: 3-bromopiperidine-2,6-dione can be treated with sodium hydroxide to form 3-hydroxypiperidin-2-one.
Uses of 3-Hydroxypiperidin-2-one in the Chemical Industry
3-Hydroxypiperidin-2-one has a wide range of applications in the chemical industry due to its unique molecular structure and properties.
Some of the key applications of 3-hydroxypiperidin-2-one include:
- As an intermediate in the production of pharmaceuticals: 3-hydroxypiperidin-2-one is used as an intermediate in the production of various pharmaceuticals, including neuromuscular blockers and anti-inflammatory drugs.
- As a reagent in organic synthesis: 3-hydroxypiperidin-2-one is used as a reagent in organic synthesis reactions, such as in the formation of amides, imines, and other organic compounds.
- In the production of dyes and pigments: 3-hydroxypiperidin-2-one is used in the production of certain dyes and pigments, such as in the production of azo dyes and phthalocyanine pigments.
- In the production of plastics and resins: 3-hydroxypiperidin-2-one is used in the production of certain plastics and resins, such as in the production of polyurethanes and epoxy resins.
- In the production of cosmetics and personal care products: 3-hydroxypiperidin-2-one is used in the production of cosmetics and personal care products, such as in the formulation of sunscreens and moisturizers.
Overall, 3-hydroxypiperidin-2-one is a versatile chemical compound that has a wide range of applications in the chemical industry.
Its unique molecular structure and properties make it a valuable intermediate in the production of