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The Chemical Industry and 3,6-Dichloro-4-(4-Pyridinyl)Pyridazine: An Overview
The chemical industry has played a crucial role in shaping modern society, providing the building blocks for a wide variety of products, from pharmaceuticals to plastics.
As the industry continues to grow and evolve, new compounds and chemical processes are constantly being developed, and 3,6-dichloro-4-(4-pyridinyl)pyridazine is one such compound that has garnered significant attention in recent years.
What is 3,6-Dichloro-4-(4-Pyridinyl)Pyridazine?
3,6-dichloro-4-(4-pyridinyl)pyridazine, also known as TMPyP, is a organic compound that belongs to the class of heterocyclic compounds.
Specifically, it is a derivative of pyridazine, which is a six-membered aromatic heterocycle that contains a nitrogen atom.
TMPyP contains two chlorine atoms attached to the 3,6 positions of the pyridazine ring, and a 4-pyridinyl group attached to the 4 position.
This compound is solid at room temperature, with a melting point of around 220-222 °C and a boiling point of around 523 K.
TMPyP is soluble in organic solvents such as ethanol and acetonitrile but insoluble in water.
It has been used as a intermediate for the production of agrochemicals, pharmaceuticals, and research chemicals.
Uses of 3,6-Dichloro-4-(4-Pyridinyl)Pyridazine
TMPyP has found use in a variety of applications due to its unique chemical properties.
One of the primary uses of TMPyP is as an intermediate in the production of agrochemicals.
It can be converted into other compounds, such as chloropyrifos, which is an insecticide used to control pests in crops such as rice and corn.
TMPyP has also been studied for its potential use in pharmaceuticals, particularly as an anti-inflammatory and antioxidant agent.
Additionally, it has been used as a building block for the synthesis of other heterocyclic compounds, and as a research chemical in studies of its own properties and reactions.
Production and Synthesis of 3,6-Dichloro-4-(4-Pyridinyl)Pyridazine
The production of TMPyP involves several steps, starting with the synthesis of 2-chloro-4-nitroaniline, which is then transformed into 2-chloro-4-nitro pyridine.
This intermediate is then reacted with acetamide in the presence of a strong acid catalyst to form N-acetyl-2-chloro-4-nitro pyridine.
This compound is then hydrolyzed using a strong base to form the corresponding amine, which is then reduced to form the final product, TMPyP.
This process can be a bit dangerous and should be carried out with proper safety equipment and under the guidance of experienced chemists.
Toxicity and Safety
Like many chemicals, TMPyP has the potential to be toxic if handled improperly.
It is classified as a Category 2 carcinogen by the International Agency for Research on Cancer (IARC), meaning that it is possibly carcinogenic to humans.
Prolonged exposure to the vapor or mist of TMPyP has been reported to cause irritation of the eyes, nose, and throat, and can lead to coughing and difficulty breathing.
It is also noted that TMPyP is highly flammable and can ignite or explode when coming into contact with open