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Introduction:
2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) is a novel drug candidate that has shown promise in the treatment of various diseases, including cancer and neurological disorders.
This compound is a synthetic molecule that has been designed to target specific biological pathways in the body, with the goal of eliciting a therapeutic effect.
Chemical Structure:
The chemical structure of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) is quite complex, with a total of 21 atoms in its structure.
The molecule consists of a benzisothiazole ring, an indole ring, a piperazine ring, and several other functional groups, including a chlorine atom and a hydroxyl group.
This complex structure is likely responsible for the diverse range of biological activities displayed by this compound.
Synthesis:
The synthesis of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) involves several steps, including the synthesis of the individual components of the molecule.
The synthesis of this compound requires advanced chemical synthesis techniques and an understanding of the underlying chemical reactions involved in the synthesis process.
Purification:
After the synthesis of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1), the crude product must be purified to remove any impurities that may have been introduced during the synthesis process.
This purification process typically involves several steps, including acid-base reactions, crystallization, and chromatography.
Characterization:
The characterization of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) involves several techniques, including spectroscopy, spectrometry, and imaging.
These techniques are used to determine the physical and chemical properties of the compound, such as its chemical composition, molecular structure, and molecular weight.
Pharmacokinetics:
The pharmacokinetics of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) have been studied in animal models and in human clinical trials.
These studies have shown that the compound has a high oral bioavailability, with significant amounts of the compound being absorbed into the bloodstream after oral administration.
The compound is also highly bound to plasma proteins, with a relatively low volume of distribution.
The compound has a short half-life in the body, with the majority of the compound being metabolized by enzymes in the liver.
Toxicity and Side Effects:
The toxicity and side effects of 2H-Indol-2-one, 5-[2-[4-(1,2