-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
2-Isobutyl-3-methylpyrazine is a chemical compound that is commonly used in the fragrance and flavor industries.
It has a distinctive, floral and fruity odor with a slightly spicy undertone, making it a popular ingredient in perfumes, soaps, shampoos, and other personal care products.
In the chemical industry, it is used as a starting material for the synthesis of other chemicals, such as pharmaceuticals and agrochemicals.
The production of 2-isobutyl-3-methylpyrazine involves several steps, including the synthesis of its precursor 2-isobutyl-3-methylpyrazine-5-carboxylic acid, followed by its hydrolysis to yield the final product.
The synthesis of 2-isobutyl-3-methylpyrazine-5-carboxylic acid involves the condensation of 2-isobutyl-3-methylpyrazine with cyclohexanecarbonitrile in the presence of a catalyst, such as hydrochloric acid.
The hydrolysis of 2-isobutyl-3-methylpyrazine-5-carboxylic acid is carried out by treating the acid with water in the presence of a strong acid catalyst, such as sulfuric acid.
The resulting product is then purified by crystallization or chromatography to yield pure 2-isobutyl-3-methylpyrazine.
The synthesis of 2-isobutyl-3-methylpyrazine can also be accomplished through other routes, such as the reduction of 2-isobutyl-3-methylpyrazine-4-carboxylic acid, the condensation of 2-isobutyl-3-methylpyrazine with acrylic acid, or the reaction of 2-isobutyl-3-methylpyrazine with sodium hydroxide to yield the sodium salt, which can then be hydrolyzed to the free acid.
In addition to its use in the fragrance and flavor industries, 2-isobutyl-3-methylpyrazine has also been found to have insecticidal properties.
Studies have shown that it is toxic to various insects, including the adult stage of the soybean aphid, the greenhouse whitefly, and the western flower thrips.
It is therefore being considered as a potential ingredient in insecticides for use in agriculture.
The use of 2-isobutyl-3-methylpyrazine in the production of other chemicals, such as pharmaceuticals and agrochemicals, has also been explored.
It has been shown to act as a precursor for the synthesis of various drugs, such as antihistamines and antipsychotics, as well as a variety of herbicides and pesticides.
The production of 2-isobutyl-3-methylpyrazine is a well-established process in the chemical industry, and its unique odor and potential insecticidal properties make it a valuable raw material for various applications.
As research continues into its potential uses, it is likely that the demand for this compound will continue to grow.
In conclusion, 2-isobutyl-3-methylpyrazine is an important chemical compound widely used in the fragrance, flavor, and chemical industries.
Its synthesis involves several steps, and there are several methods available for its production.
The compound has been found to have insecticidal properties, and it is also a potential starting material for the synthesis of various other chemicals, such as pharmaceuticals and agrochemicals.
As research continues, it is likely that the use of 2-is