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In the chemical industry, 2-chloro-pyrimidin-4-ylmethyl)-ethyl-amine (CCPE) is a commonly used intermediate in the synthesis of various chemicals and pharmaceuticals.
It is an organic compound with a distinct chemical structure and properties that make it suitable for a variety of applications.
CCPE is synthesized through a multi-step process that involves several chemical reactions.
The synthesis process can be broken down into the following steps:
- The first step in the synthesis of CCPE involves the conversion of aniline, a readily available starting material, into 4-chloro-2-methyl-aniline through a series of chemical reactions.
- The next step in the synthesis involves the reaction of 4-chloro-2-methyl-aniline with methyl iodide to form 4-chloro-2-methyl-aniline methyl iodide.
- The resulting product from the previous step is then reacted with hydroiodic acid to form 4-chloro-2-methyl-aniline hydroiodide.
- The hydroiodide group in the previous step is then converted into an amine group through a process known as hydrolysis.
This reaction is carried out using a strong acid such as hydrochloric acid. - The final step in the synthesis of CCPE involves the reaction of the resulting product from the previous step with ethylamine to form the target compound, 2-chloro-pyrimidin-4-ylmethyl)-ethyl-amine.
The synthesis of CCPE requires the use of various chemical reagents and solvents, as well as the application of different reaction conditions.
The choice of solvent and conditions used in the synthesis can have a significant impact on the yield and purity of the final product.
CCPE is a versatile intermediate that can be used in the synthesis of a variety of chemicals and pharmaceuticals.
One of the main applications of CCPE is in the synthesis of anti-inflammatory drugs, such as celecoxib and valdecoxib.
These drugs are commonly used to treat conditions such as arthritis and pain.
CCPE is also used as an intermediate in the synthesis of antiviral drugs, such as oseltamivir and zanamivir, which are commonly used to treat influenza.
In addition, CCPE is used in the synthesis of other pharmaceuticals, such as anti-depressants and anti-cancer drugs.
In addition to its use in pharmaceuticals, CCPE is also used in the production of other chemicals, such as surfactants, fragrances, and plastics.
The compound is also used in research and development, particularly in the field of medicinal chemistry, where it is used as a building block for the synthesis of new compounds with potential therapeutic applications.
Despite its widespread use in the chemical industry, CCPE is not without its hazards.
The compound is classified as a moderate health hazard, and exposure to the vapor or liquid can cause irritation to the eyes, skin, and respiratory system.
Proper handling and disposal of the compound are essential to prevent harm to workers and the environment.
In conclusion, 2-chloro-pyrimidin-4-ylmethyl)-ethyl-amine (CCPE) is a versatile intermediate that is widely used in the synthesis of various chemicals and pharmaceuticals.
Its unique chemical structure and properties make it suitable for a variety of applications, and its widespread use in the chemical industry reflects its importance as a building block for the synthesis of new compounds.
However, its use requires proper handling and disposal to prevent harm to workers and the environment