The Instruction of 2-Chloro-7-iodothieno[3,2-d]pyrimidine

The 2-Chloro-7-iodothieno[3,2-d]pyrimidine, also known as CAS 85868-64-4, is an important intermediate in the pharmaceutical and chemical industry.
It is used as a building block for the synthesis of various drugs and other chemicals.

The production process of 2-Chloro-7-iodothieno[3,2-d]pyrimidine typically involves several steps, including the synthesis of the individual components and their subsequent reaction to form the final product.

The synthesis of 2-Chloro-7-iodothieno[3,2-d]pyrimidine typically starts with the reaction of thiophene-2-carboxaldehyde and 2-bromo-7-iodo-thiazole in the presence of a strong acid catalyst.
This reaction forms a ketone, which is then reduced to an alcohol using a reducing agent such as lithium aluminum hydride.

Next, the alcohol is converted into an amide by reaction with a carboxylic acid, such as acetic acid.
This amide is then hydrolyzed to an amine by treatment with a strong base, such as sodium hydroxide.

The amine is then reacted with chloroform to form a diazo compound, which is then iodinated by treatment with a solution of iodine and acetone.
Finally, the resulting 2-Chloro-7-iodothieno[3,2-d]pyrimidine is isolated and purified by known techniques.

2-Chloro-7-iodothieno[3,2-d]pyrimidine is a highly reactive intermediate and is typically used as a building block for the synthesis of other chemicals and drugs.
It has been used in the synthesis of several drugs, including some anti-malarial and anti-viral compounds.

The production of 2-Chloro-7-iodothieno[3,2-d]pyrimidine is a complex process that requires careful control of the reaction conditions to ensure the desired product is obtained.
The use of high-purity reagents and careful purification of the final product is also important to ensure the quality of the final product.

In conclusion, 2-Chloro-7-iodothieno[3,2-d]pyrimidine is an important intermediate in the pharmaceutical and chemical industry and is used in the synthesis of several drugs and other chemicals.
The production process involves several steps, including the synthesis of the individual components and their subsequent reaction to form the final product.
The production of 2-Chloro-7-iodothieno[3,2-d]pyrimidine requires careful control of the reaction conditions and the use of high-purity reagents to ensure the quality of the final product.