The Production and Use of 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea in the Chemical Industry

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea, commonly referred to as CYP-urea, is an important intermediate in the production of various chemicals and pharmaceuticals.
This compound has a wide range of applications and is highly valued for its unique properties.

Overview of 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea is a white to off-white solid that is soluble in water and many organic solvents.
It has a melting point of around 170-175°C and a boiling point of around 270-275°C.
The molecular formula for this compound is C₁₂H₁₁Cl₂N₃O₂ and it has a molecular weight of 283.
66 g/mol.

The Structure of 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

The structure of 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea is characterized by a cyclopropyl group, a urea group, and a phenyl group.
The cyclopropyl group consists of a six-membered ring with three carbon atoms and three hydrogen atoms.
The urea group consists of a carbon atom, a nitrogen atom, and a hydrogen atom.
The phenyl group consists of a six-membered aromatic ring with six carbon atoms and five hydrogen atoms.

The Production of 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea is typically produced via a series of chemical reactions.
The starting material is 2-chlorobenzaldehyde, which is treated with sodium hydroxide to form 2-hydroxybenzaldehyde.
This compound is then treated with cyclopropyl carbamate to form the cyclopropylurea derivative.
The resulting compound is then hydrolyzed using a strong acid, such as hydrochloric acid, to produce 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea.

Applications of 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea has a wide range of applications in the chemical industry.
It is a versatile building block for the synthesis of a variety of chemicals and pharmaceuticals.
Some of the most common applications of this compound include:

• Intermediate for the production of antihistamines and antiallergic drugs
• Intermediate for the production of dyes and pigments
• Intermediate for the production of agricultural chemicals and fertilizers
• Building block for the synthesis of polymers and other materials

Advantages of 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea has several advantages that make it a popular choice for a wide range of applications.
Some of the key