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    Home > Biochemistry News > Biotechnology News > The Institute of Hydrobiology has made important progress in the study of fish adapting to the extreme environment of the Qinghai-Tibet Plateau

    The Institute of Hydrobiology has made important progress in the study of fish adapting to the extreme environment of the Qinghai-Tibet Plateau

    • Last Update: 2021-12-31
    • Source: Internet
    • Author: User
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    Institute of Hydrobiology, Chinese Academy of fish systematics and biogeography Research Group researchers by Triplophysa , crack abdominal fish , mudfish Select Committee fish three kinds of fish and low-altitude plateau of fish in comparative genomics studies to explore the three The molecular level convergent evolution of large plateau fishes in the process of adapting to the extreme environment of the Qinghai-Tibet Plateau


    Research results show that : 1 ) the three low altitude plateau of fish and fish were seen in the rate of evolution compared to significantly accelerate the phenomenon; 2 ) plateau a fish were detected to 368 genes by the positive selection, and significantly Concentrated in the pathways of energy and hypoxic metabolism; 3 ) A large number of parallel amino acid substitutions at the molecular level have been identified in the three plateau fishes, and more importantly, nearly half of these amino acid parallel substitution sites are plateau fishes Unique ; 4 ) The results of functional experiments show that the key gene VHL of the hypoxia regulation pathway is significantly lower than that of low-altitude fish under normal oxygen conditions, but higher than that of low-altitude fish under low oxygen conditions.


    This research was completed by associate researcher Yang Liandong and others.


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