The Health and Health Commission then notified some institutions of the results of medical scientific research integrity cases

Investigation and handling results of medical scientific research integrity cases in some institutions (September 1, 2021)

Investigation and handling results of medical scientific research integrity cases in some institutions (September 1, 2021) Investigation and handling results of medical scientific research integrity cases in some institutions (September 1, 2021)

The investigation and handling results of medical scientific research integrity cases recently publicly notified by some medical institutions affiliated to health administrative departments are reproduced as follows:

1.
The paper "Kaempferol suppresses proliferation but increases apoptosis and autophagy by up-regulating microRNA-340 in human lung cancer cells" published by Han Xue from Dalian Central Hospital in Liaoning Province as the first author.
After investigation, the paper has been bought and sold, and before submission The informed consent of all authors was not obtained in accordance with the standard procedures
.

Dalian Central Hospital of Han Xue treated as follows: given an administrative warning punishment ; credited to research integrity management system for five years; five years to declare canceled research projects, science and technology awards, Talents Scheme, outstanding party member , to declare all kinds of bases, job promotion, Qualifications for promotion and appointment of professional titles; it is recommended that Dalian Medical University cancel the qualification of master's tutors and not apply again within five years; withdraw the excellent paper awards issued by the hospital; conduct scientific research integrity admonitions and write a scientific research integrity commitment letter

Punish party members

(Notification link: https:// style="text-indent:2em"> 2.
The paper "Ailanthone exerts anticancer effect by up-regulating miR-148aexpression in MDA-MB-231 breast cancer cells and inhibiting proliferation, migration and invasion" published by Gao Wei from Dalian Central Hospital in Liaoning Province as the first author and corresponding author, After investigation, there was a sale of papers
.

Dalian Central Hospital of Gao Wei treated as follows: given the party warning sanction ; credited to research integrity management system for five years; cancel research projects declared five years, science and technology awards, Talents Scheme, outstanding party member , to declare all kinds of bases, job promotion Qualifications for promotion of professional titles and appointments; Withdrawal of awards for outstanding papers issued by the hospital; Conduct conversations on scientific research integrity and admonishment, and write a scientific research integrity commitment letter

Punish party members

(Notification link: https:// style="text-indent:2em"> 3.
The paper "Long non-coding RNA TUG1 alleviates LPS-induced injury of PC-12cells by down-regulating microRNA-127" published by Cao Jin as the corresponding author and Zheng Huajiang as the first author of the Sixth Hospital of Ningbo City, Zhejiang Province.
, The first author Zheng Huajiang entrusted a third party to write, and the corresponding author Cao Jin was unaware of the writing and submission of the paper, but after learning of the publication of the paper, he did not ask the journal to revoke the signature of the corresponding author
.

The Sixth Hospital of Ningbo City shall deal with relevant responsible personnel:

1.
Suspend the promotion of Zheng Huajiang's professional and technical positions for 5 years, cancel his application for science and technology plan projects (special projects, funds) and science and technology award qualifications for 5 years, cancel his qualifications as experts in dissertations, topics, and science and technology awards for 5 years, and give him scientific research integrity warnings , Administrative warnings , deductions and penalties for three months of bonuses;

Sanction

2.
Cancel Cao Jin's application for science and technology plan projects (special projects, funds) and science and technology award qualifications for 1 year
.

(Notification link: http:// style="text-indent:2em"> 4.
The paper "Physcion 8-O-β-glucopyranoside exerts anti-tumor activity against non-small celllung cancer by targeting PPARγ" published in 2019 by Zhou Jiafeng as the corresponding author and Du Youyi as the first author of Lishui Central Hospital, Zhejiang Province, After investigation, the paper involved academic misconduct such as forging and falsifying research data and diagrams
.

Lishui Central Hospital shall give the following treatments to relevant responsible personnel:

1.
Conduct admonishment talks with Zhou Jiafeng and Du Youyi, cancel the application or application for science and technology plan projects (special projects, funds, etc.
), science and technology awards, and science and technology talent title qualifications within five years, and postpone the promotion of professional and technical positions for two years;

2.
Criticize and educate other authors Li Yuan, Sun Lei, Lu Zhuqing, and Sun Debin, cancel applications or applications for science and technology plan projects (special projects, funds, etc.
), science and technology awards, and science and technology talent titles within one year, and cannot be promoted to professional and technical positions that year
.

(Notification link: http:// style="text-indent:2em"> 5.
The paper "MiR-203 regulates DJ-1 expression and affects proliferation, apoptosis and DDP resistance of pancreatic cancer cells" published by Dong Zhihui as the corresponding author and Du Shilin as the first author of Luoyang Central Hospital in Henan Province, after investigation, was approved by Du Shilin.
The third-party organization wrote and submitted the manuscript on its behalf, and did not inform all the authors before submitting the manuscript, there are academic misconducts such as writing and submitting the manuscript and improper attribution
.

Luoyang Central Hospital made the following treatments to relevant responsible personnel:

1, the first author of Du Fu Lin to give admonishing remarks, warned punishment , to give criticism, ordered to make a deep examination, suspend declaration of financial support for research projects five years, to suspend the declaration senior title five years, the abolition of personal qualifications Pingyoupingxian 5 years;

Sanction

2, Corresponding Author Dong Zhihui give admonishing remarks, warned punishment , to give criticism, ordered to make a profound examination;

Sanction

3.
To other authors Xu Lingyan, Gao Peng, Liu Qingsheng, Lu Fangfang, Mo Zheheng, Fan Zhenzhen, Cheng Xinling to talk about scientific research integrity;

4.
The paper is retracted, and all related applications of the paper are prohibited
.

(Notification link: http:// style="text-indent:2em"> 6.
The paper "Physcion8-0-B-glucopyranoside exhibits anti-growth and anti-metastatic activities in ovarian cancer by down regulating miR-25" published by He Shehong as the corresponding author and Xue Congling as the first author of Luoyang Central Hospital, Henan Province, was investigated , Xue Congling personally wrote and submitted the manuscript on her behalf through a third-party agency, and did not inform all the authors before submitting the manuscript, which involved academic misconduct involving proxy submission and improper attribution
.

Luoyang Central Hospital made the following treatments to relevant responsible personnel:

1, the first author Xue Congling give admonishing remarks, warned punishment , to give criticism, ordered to make a deep examination, suspend declaration of financial support for research projects five years, Dr.
suspend the declaration, Master Instructor five years, slow appointed senior title 5 years, Collect the reimbursed page expenses and reward income, and cancel the qualification for personal evaluation for 5 years;

Sanction

2, Corresponding Author HE gives red admonishing remarks, warned punishment , to give criticism, ordered to make a profound examination;

Sanction

3.
To other authors Liu Honggai, Li Bingyi, and Yue Qingfen to talk about scientific research integrity;

4.
The paper is retracted, and all related applications of the paper are prohibited
.

(Notification link: http:// style="text-indent:2em"> 7.
The paper "Alpinumisoflavone causes DNA damage in Colorectal Cancer Cells viablocking DNA repair mediated by RAD51" published by Li Dong from the Oilfield General Hospital of Puyang City, Henan Province as the corresponding author and the first author.
After investigation, there are trading data and improper attribution
.

Puyang Oilfield General Hospital retracted the manuscript of this paper, and dealt with the participants as follows:

1, to give Dong (first author, corresponding author) warning punishment , be research letter admonishing remarks, the hospital informed criticism, canceled five years to apply scientific research, science and technology awards, the title of scientific and technological personnel, professional and technical job promotion and individual units of the first assessment And other qualifications;

Sanction

2.
Give Li Genqu (three works), Meng Yan (four works), Jin Yanghong (five works), Shang Shuang (six works), and Li Yanjie (seven works) to talk about scientific research integrity, and cancel the 5-year application or application for science and technology Qualifications for planned projects (special projects, funds, etc.
), scientific and technological awards, scientific and technological talent titles, promotion of professional and technical positions, and individual evaluation of units;

3.
Cancel Li Xiaoyan's (second work) one-year application or application for science and technology plan projects (special projects, funds, etc.
), science and technology awards, scientific and technological talent titles, professional and technical post promotion, and personal evaluation of the unit
.

(Notification link: https:// style="text-indent:2em"> 8.
The paper "LncRNA MALAT1 regulates sepsis-induced cardiac inflammation anddysfunction via interaction with miR-125b and p38 MAPK/NFκB" published by Yan Xuetao as the corresponding author and Chen Hu as the first author from the Maternity and Child Health Care Hospital of Baoan District, Shenzhen, Guangdong Province.
, Is commissioned by a third-party organization to conduct experimental operations.
There are traces of modification in the pictures in the article, and academic misconduct involving fraudulent pictures
.

The Maternity and Child Health Hospital of Baoan District, Shenzhen shall deal with the relevant responsible personnel as follows:

1.
Conduct scientific research integrity admonishment conversations with the authors of the papers, request to withdraw the papers and withdraw the rewards;

2.
Suspend the first author of the thesis Chen Hu and communication author Yan Xuetao from applying for the qualifications of scientific research projects at all levels for 5 years, request to cancel the senior title of the first author Chen Hu, and suspend the admission of communication author Yan Xuetao for 5 years;

3.
Suspend the signed authors Wang Xiaoyun, Cheng Xiaoli and Zheng Wenzhong from applying for the qualifications of scientific research projects at all levels for one year
.

(Notification link: http:// style="text-indent:2em"> 9.
The paper "Downregulation of lncRNA TUG1 contributes to the development of sepsis-associated acute kidney injury via regulatingmiR-142-3p/sirtuin 1 axisand modulating NF-κBpathway" published by Hong Chengying as the corresponding author and Liu Xiaodi as the first author from Shenzhen People's Hospital of Guangdong Province "After investigation, it was a third-party organization that conducted experimental operations.
There are many similarities in the pictures in the article, which involve academic misconduct such as fake pictures
.

Shenzhen People's Hospital shall deal with the relevant responsible personnel as follows:

1.
Conduct a scientific research integrity admonition talk to the corresponding author Hong Chengying, publicly report criticisms within the hospital, and cancel the qualifications for applying for or applying for scientific research projects (special projects, funds, etc.
), scientific and technological awards, scientific and technological talent titles, and professional and technical post promotion within three years;

2.
Conduct scientific research integrity admonishment conversations and public criticisms of the hospital's internal public announcements to the first author Liu Xiaodi and other authors Wu Shipin, Yang Zhi, Cao Lin, Song Tongwei, Yang Ying and other secondary responsible authors
.

(Notification link: https:// style="text-indent:2em"> 10.
The paper "Propofol weakens hypoxia-aroused apoptosis and autophagy via elevating microRNA-137 in neurocytes" published by Zeng Yuan as the corresponding author and Chang Jianhua from the Shaanxi Provincial People's Hospital as the first author.
Third-party writing and submission
.

The Third Hospital of Xi’an City made the following actions for the relevant responsible person Zeng Yuan: give warnings ; conduct scientific research integrity admonishment conversations; submit personal written inspections and notify and criticize; postpone the application of professional and technical job promotion qualifications for 5 years; stop applying for all types of scientific research funds 5 years; stop using the in-house scientific research platform for 5 years; deduct personal performance for 1 month; withdraw the manuscript

Punishment punishment

(Notification link: http:// style="text-indent:2em"> 11.
The paper "MicroRNA-1247 inhibits lipopolysaccharides-induced acute pneumoniain A549 cells via targeting CCchemokine ligand 16" published by Guo Jinjing from the Maternity and Child Health Hospital of Weinan City, Shaanxi Province as the corresponding author and the first author.
On behalf of the investment, other author Cheng Ying improperly signed
.

Weinan Maternity and Child Health Hospital shall deal with relevant persons in charge as follows:

1, corresponding author and first author Guo Beijing ordered retractions, conduct research integrity admonishing remarks, given the hospital administrative warning punishment , reprimand, cancel less than six years of staff rank qualifications and application or declaration science and technology projects (projects, funds, etc.
), Science and technology awards, the title of science and technology talents;

Sanction

2.
Talk to other authors Cheng Ying on scientific research integrity, report criticism in the hospital, and cancel the qualification for promotion within 1 year
.

(Notification link: http:// style="text-indent:2em"> 12.
The paper "MiR-155 regulates lymphoma cell proliferation and apoptosisThroughtargetingSOCS3/JAK-STAT3 signaling pathway" published by Sun Xiaochen as the corresponding author and Li Xiaodong as the first author from the People's Hospital of Yan'an City, Shaanxi Province.
Submission, the corresponding author, and other authors improperly signed
.

The People's Hospital of Yan'an City shall deal with the relevant persons in charge as follows:

1, the first author Li Xiaodong bear the main responsibility for the integrity of scientific research to be admonishing remarks, warning given administrative punishment , the hospital reprimand, revoke the use of paper awards and titles to recover bonuses, declared national ban within six years, for all kinds of Project, reward declaration, promotion title, order to withdraw the draft;

Sanction

2, Corresponding Author Sun Xiaochen improper signature, the integrity of scientific research to be admonishing remarks, giving the hospital a warning punishment , the hospital informed criticism, within three years prohibited the declaration of national, provincial and municipal various projects, incentives to declare, staff rank;

Sanction

3.
The other authors Li Xinmei and Gu Jiawei improperly signed their names and gave them scientific research integrity admonitions, and the whole hospital notified them to criticize them.
It is forbidden to apply for various national, provincial and municipal projects, award applications, and promotion titles within one year
.

 

(Notification link: http://