In recent years, with the rapid development of biological drugs and other industries, and the accelerated transformation and upgrading of the pharmaceutical industry under the new medical reform, the domestic pharmaceutical equipment industry has ushered in a new round of development opportunities, in this context, the head pharmaceutical machine enterprises represented by Chutian Science and Technology, Dongfulong, etc.
have seized the opportunity, through continuous increase in research and development investment, constantly enrich product categories, optimize product structure, and actively layout new tracks such as biopharmaceuticals and vaccines to meet the needs of
downstream localization replacement.
Pharmaceutical equipment industry (Image source: Pharmaceutical Network)
According to the annual report data of two representative leading pharmaceutical machine companies, Chutian Technology and Dongfulong, in Q1~3 of 2020/2021/2022, the annual R&D expenses of Dongfulong were 156 million yuan/285 million yuan/232 million yuan, respectively, showing an overall improvement trend; The annual R&D expenses of Chutian Technology are 288 million yuan/488 million yuan/375 million yuan, respectively, and the company's R&D investment expenses have accounted for about
10% of the annual revenue in recent years.
The increase in R&D expenses of the above two enterprises is mainly due to the increase in R&D investment, the expansion of R&D personnel, and the increase in the number of R&D projects
.
The 2021 annual report shows that the company's main research and development projects include a series of filling equipment, biological drug equipment, etc.
, and intends to achieve the goals of breaking foreign technology monopoly, benchmarking European and American standards, reducing consumption and costs, substituting imported equipment, enhancing production compliance, real-time monitoring, overall solutions, green environmental protection, automation and other goals
.
In recent years, the sudden epidemic has further increased the importance of the biomedical industry, in order to promote the development of the biomedical industry, the state has issued a series of policies to support and encourage industrial development, and many places have also regarded biomedicine as a strategic industry
to promote high-quality economic development.
In response to the 14th Five-Year Plan of the National Pharmaceutical Industry and help the development of the biological industry, Chutian Technology has also invested in a number of R&D projects, including continuous inactivation equipment, microcarrier suspension culture bioreactors, animal cell culture reactors), GMP cell drug workstations, etc
.
The head enterprise of domestic freeze dryer Dongfulong also disclosed the main research and development projects in the 2021 annual report, including freeze dryer products, cell equipment, etc.
, the goals to be achieved include integration, integration, automation, intelligence, quality and efficiency, energy saving, cross-contamination reduction, high-speed continuous production, domestic substitution of imported products, reduction of labor costs, real-time monitoring, etc.
, in order to achieve product iterative upgrading, enhance the competitiveness of the company's products, enter the world, etc.
, and bring new profit growth points to the company
。
Popular subdivisions such as vaccines and macromolecular drugs are gaining the increased layout
of Dongfulong.
In the field of vaccines, with the rapid development of China's vaccine industry and the gradual increase in investment in new product development, China's vaccine regulatory system has successfully passed the certification of the World Health Organization, the country's investment in public health services including disease prevention and control and vaccination has been increasing, people's awareness of vaccination has been continuously improved, and aging has intensified, etc.
, the market capacity of the domestic vaccine industry will continue to expand
。 In order to strengthen the national vaccine industry chain, Dongfulong is developing vaccine core equipment based on national needs and continuously expanding its product line, and related R&D projects include disposable cell expansion system products, disposable biological reaction bags (MB), and disposable stirring bags (MM).
。 In the field of macromolecular drugs, in order to open up the market in the production direction of macromolecular drugs and develop the company's brand establishment, Dongfulong has invested in R&D projects such as Chinese hamster ovarian cell (CHO-1) serum-free medium, MSCs (mesenchymal stem cells) serum-free medium, performance improvement of Protcin L affinity chromatography media, and development of high-load Protcin G affinity chromatography media
.
It is worth mentioning that in the era of digitalization and intelligence, the pharmaceutical industry is accelerating to embrace new trends, and production compliance is becoming more and more valued by pharmaceutical companies.
For example, the biological or sterile preparation production execution system (MES) invested in the research and development of Chutian Technology aims to enhance production compliance and improve enterprise production efficiency, effectively improve paperless office capabilities and production transparency management level, reduce production costs, enhance enterprise information sharing capabilities and mine the value of
production data.
In addition, domestic substitution is a major trend in the development of the domestic pharmaceutical equipment industry, and it is also one of the research and development goals of
Chutian Technology and Dongfulong.
The industry believes that as the R&D investment of domestic pharmaceutical equipment enterprises continues to increase, product performance continues to improve, brand influence is gradually formed, the pace of domestic substitution will accelerate, and the market structure is expected to usher in a reshuffle
.
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