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    Home > Active Ingredient News > Study of Nervous System > The gospel of diabetic foot?

    The gospel of diabetic foot?

    • Last Update: 2021-12-04
    • Source: Internet
    • Author: User
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    Since 1980, the prevalence of diabetes has quadrupled.
    In 2014, the number of diabetes cases reached 422 million.
    The main reason for the increase in the incidence of diabetes is the increase in the incidence of diabetes in developing countries
    .


    Researchers predict that this number will further increase in the next few years, which is directly related to the increasing prevalence of obesity, sedentary life>


    diabetes

    The costs of diabetic neuropathy, foot ulcers, and lower limb amputations are already huge.
    According to reports, in addition to the cost of diabetes itself, the burden on public and private payers ranges from US$9 billion to US$13 billion
    .

    The cost and health impact of lower extremity complications caused by diabetes is an increasingly heavy social burden
    .

    Lower extremity nerve decompression can reduce the symptoms of neuropathy and the concomitant risk of diabetic foot ulcers and amputation
    .

    In order to evaluate the health and economic effects of this operation, the researchers studied the cost-effectiveness of this intervention compared with current non-surgical treatments
    .

    Figure 1 Source of the article

    In order to evaluate the incremental cost and effect of lower extremity nerve decompression over a 10-year period, the researchers developed a Markov model to simulate the onset and progression of diabetic foot disease in diabetic and neuropathic patients undergoing lower extremity nerve decompression surgery.
    Compared with the group receiving non-surgical treatment
    .


    The study assessed patients' average survival time, health-related quality of life , presence or risk of lower extremity complications, and hospitalization costs


    Quality of Life

    Lower extremity nerve decompression surgery increased life expectancy (88369.
    5 years vs.
    86513.
    6 years), improved quality-adjusted life expectancy (67652.
    5 years vs.
    64082.
    3 years), and reduced the incidence of foot complications compared with current care ( 490 years old to 1087 years old)
    .

    Table 1 The stimulus results of a 10-year cohort comparing the incidence of lower extremity complications of the two strategies

    Figure 2 Cost-benefit acceptability curve
    .

    The results of incremental cost-benefit analysis show that each quality-adjusted life year can get 5,9279.
    6 euros, which is lower than the critical threshold in the Netherlands, that is, the cost of each quality-adjusted life year is less than 80,000 euros.

    Lower extremity nerve decompression surgery can improve survival rate and reduce diabetic foot complications.
    Compared with current treatments, it saves costs and cost-effectiveness, and brings considerable social and economic benefits to society
    .

    Lower extremity nerve decompression surgery can improve survival rate and reduce diabetic foot complications.
    Compared with current treatments, it saves costs and cost-effectiveness, and brings considerable social and economic benefits to society
    .


    And this is related to long-term higher survival rates and lower morbidity (better quality of life)
    .


    Large-scale prospective studies help to improve the model, especially the transition probability and utility of lower limb nerve compression-related health states


    The general conclusion is that diabetic patients with neuropathy often have treatable nerve compression syndrome, which can be treated surgically, which provides guidance for clinicians
    .


    By checking whether the patient has nerve compression, treatment options that affect the long-term prognosis can be selected


    Diabetic patients with neuropathy often have treatable nerve compression syndromes that can be treated surgically, which provides guidance for clinicians


    Reference source:

    Rinkel Willem D,Franks Billy,Birnie Erwin et al.


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