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Picture: Professor Justin O'Sullivan is the deputy director of the Liggins Institute at the University of Auckland
New research shows that lung infections can trigger type 1 diabetes, an autoimmune state that prevents people from producing enough insulin to keep blood sugar within the normal range
This led to an unexpected discovery: the greatest impact on lung genes
Doctoral students Daniel Ho and Denis Nyaga are the main researchers of the project
"Machine learning allows us to model the DNA of thousands of people together with relevant biological information, which we can not be detected by other means, because the data is too much for us"
Diabetes is proliferating globally and has proven to be one of the major health challenges of the 21st century
Researchers sequenced part of the child's DNA when it was born, and can use 67 genetic variants to predict whether the child will develop type 1 diabetes at the age of 5 with an accuracy rate of more than 90%
Article title
Identifying the lungs as a susceptible site for allele-specific regulatory changes associated with type-1 diabetes risk
