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    Home > Active Ingredient News > Drugs Articles > The general order of freeze-dried drugs in Sihuan freeze-dried pharmaceutical freeze dryer

    The general order of freeze-dried drugs in Sihuan freeze-dried pharmaceutical freeze dryer

    • Last Update: 2022-04-29
    • Source: Internet
    • Author: User
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    Sihuan freeze-drying pharmaceutical freeze-drying machine adopts vacuum freezing method in the research and development of pharmaceutical preparations to preserve the active ingredients of drugs.
    In the process of experimental research and development, high-performance freeze-drying equipment is selected to meet the requirements of freeze-drying process conditions and data research and development
    .

    Sihuan freeze-drying pharmaceutical freeze-drying machine has very outstanding advantages and characteristics: a) The liquid medicine is divided before freezing, and the dosage is accurate; b) It is dried at low temperature, which can keep the heat-sensitive substances in the dried medicine; c) When dried under low pressure, the dried medicine is not easy to be oxidized and deteriorated, and at the same time, it can be sterilized due to lack of oxygen or inhibit the vitality of some bacteria; d) When frozen, the dried medicine can form a "skeleton", which can maintain its original shape after drying, forming a Porous structure and basically unchanged color; e) good rehydration, freeze-dried drugs can quickly absorb water and restore to the state before freeze-drying; f) thoroughly dehydrated, suitable for long-distance transportation and long-term storage
    .

    The freezing process during freeze-drying is very important because the morphology and size of ice crystals formed during freezing and the degree of vitrification affect not only the subsequent drying rate, but also the quality of the lyophilized drug product
    .

    Therefore, problems such as formula, freezing rate, freezing method, and whether to anneal must be considered during the freezing process
    .

    The general order of freeze-drying medicines by Sihuan freeze-drying pharmaceutical freeze dryer: 1.
    The medicines should be subpackaged before freezing, and the dosage should be accurate; 2.
    Drying at low temperature can keep the heat-sensitive substances in the dried medicines; 3.
    When dried under low pressure, the dried medicine is not easy to be oxidized and deteriorated, and at the same time, it can sterilize or inhibit the vitality of some bacteria due to lack of oxygen; 4.
    When frozen, the dried medicine can form a "skeleton", which can maintain its original shape after drying, forming a porous structure And the color is basically unchanged; 5.
    Good rehydration, freeze-dried drugs can quickly absorb water and restore to the state before freeze-drying; 6.
    Thorough dehydration, suitable for long-distance transportation and long-term storage
    .

     
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