The formulation of wild medicinal fungi is expected to be a new antitumor drug

In December 2013, the Department of biology and pharmaceutics of the Department of rescue medicine of the Logistics College of the Chinese armed police carried out a systematic screening experiment on the antitumor activity of a variety of formulas of wild medicinal fungi, such as conidia, Inonotus obliquus, fimbriae tenuifolia, Thiobacillus, Fusarium hirsutum, Coriolus versicolor and Ganoderma lucidum The results showed that the inhibition rate of paclitaxel to cervical cancer cells was 79.69%, and the inhibition rate of wild medicinal fungi was 72.94% It is understood that paclitaxel is a highly effective, low-toxic, broad-spectrum natural anticancer drug extracted from Taxus, which is a conventional chemotherapy drug for ovarian cancer and breast cancer, and also can be used for the treatment of lung cancer, head and neck cancer, esophageal cancer, germ cell tumor, endometrial cancer, lymphoma and bladder cancer However, paclitaxel can cause side effects such as myelosuppression, immunosuppression, anaphylaxis, gastrointestinal reaction and liver dysfunction Experts from the construction and Management Committee of clinical nutrition discipline of the Ministry of Health said that compared with paclitaxel, the advantages of the formula combination of wild medicinal fungi lie in non-toxic side effects It can repair tissues and organs, improve human immunity, overcome various adverse reactions of chemotherapy drugs, effectively reduce patients' pain, and is a new direction of human treatment of tumors Related news: mushroom can prevent cervical cancer? You know mushrooms are nutritious and a low calorie diet, but now new research shows that mushrooms can also fight cancer Japan uses mushroom extracts to kill the sexually transmitted virus, which causes cervical cancer in human papillomavirus Human papillomavirus (HPV) is a common highly infectious virus that affects the skin and the body's moisturizing lining, such as the lining of the cervix, mouth and throat More than three-quarters of women are living with the virus, some of which can cause cervical cancer However, studies in the United States have found that active hexose related compounds (AHCC), an extract of Lentinus edodes, play an important role in the prevention of human papillomavirus (HPV) and other cancers In a study using mice, AHCC eradicated HPV within 90 days It also slows down the growth of cervical cancer AHCC is a common food supplement that researchers say could eventually replace the HPV vaccine "The results of this study are very encouraging," said Dr Judith Smith, associate professor of medicine at the University of Texas Health Sciences Center "Since 2008, the study has shown that the AHCC compound contained in mushroom itself may play a role in the treatment of HPV infection." AHCC plays an important role in immunotherapy It is helpful to use the immune system of human body to treat diseases Studies in humans and in the laboratory have shown that AHCC increases the number and activity of natural killer (NK) cells, dendritic cells, and cytokines that enable the body to respond effectively to infection and prevent the spread of tumors HPV DNA detected 99.7% of cervical cancer biopsies, resulting in the largest cancer inducing relationship Other types of cancer are also associated with HPV, including 95% of anal cancer, 60% of throat swelling, 65% of vaginal cancer, 50% of vulvar cancer, and 35% of penile cancer "Active hexose related compounds, AHCC, are very common nutritional supplements with good tolerance and have been used in Japan for decades," Dr Smith said Try to find a nutritional treatment for HPV infection I am very excited about this nutritional treatment "Our previous studies have shown that antiretroviral therapy has been successful in eradicating HPV infection, but we want to develop a more mild treatment because of the side effects of these drugs The findings were presented at the 45th annual meeting of the gynecological oncology society in Tampa, Florida.