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The article, recently published in Pharmacology & Therapeutics, a leading medical review journal in the field of pharmacology, documents the growth-inhibitory activity of capsaicin sustained-release drugs, including solid dispersion systems, liposomes, phospholipid complexes, and nanoparticles
"This review article provides the first comprehensive overview of capsaicin formulations in human cancer," said corresponding author Das Gupta
The nutrient capsaicin exhibits potent growth-inhibitory activity in a variety of human cancers
"Oral capsaicin has been associated with undesirable side effects such as stomach cramps, nausea, a burning sensation in the gut, and gastrointestinal irritation," said Valentovic, the study's senior author
In addition to Dasgupta and Valentovic, clinical faculty members Maria T.
This research was supported by the National Institutes of Health R15 Academic Research Advancement Award (1R15CA161491-01A1, 2R15CA161491-02, 2R15CA161491-03, R15AI151970-01 and 1r15hl145573-01), the West Virginia Network for Excellence in Biomedical Research Ideas (WV -INBRE) grant (P20GM103434) and the National Science Foundation (SURE) and West Virginia NASA National Grant Consortium
Journal Reference :
Justin C.