 Home > Biochemistry News > Biotechnology News > The first CAR-T therapy targeting BCMA was approved by the FDA for marketing

The first CAR-T therapy targeting BCMA was approved by the FDA for marketing

 Last Update: 2021-04-19
 Source: Internet
 Author: User

Tags

multiple sclerosis disease involves

cell based assays

drug classification system

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Author: cockle

On March 26, Bristol-Myers Squibb and bluebird jointly announced that the FDA has approved Abecma (idecabtagenevicleucel; ide-cel) as the first targeted chimeric antigen receptor (CAR) T cell immunity targeting B cell maturation antigen (BCMA) Therapies are used to treat adult patients with relapsed or refractory multiple myeloma.

Multiple myeloma (MM) is a malignant disease in which clonal plasma cells proliferate abnormally.

BCMA is an extremely important B cell biomarker, which is widely present on the surface of MM cells.

The FDA approval is based on data from a key Phase II clinical study code-named KarMMa.

The results of the study showed that the overall response rate (ORR) of 100 patients with evaluable efficacy was 72% (95% CI: 62-81), and 28% of patients achieved strict complete remission (sCR, 95% CI: 19%-38) %).

Note: The original text has been deleted

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.