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UCB's innovative treatment for psoriasis obtains EU approval

 Last Update: 2021-09-12
 Source: Internet
 Author: User

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Recently, UCB announced that the European Commission has approved the company's development of Bimzelx (bimekizumab) for the treatment of patients with moderate to severe plaque psoriasis suitable for systemic treatment
.

The press release states that this is the first IL-17A/IL-17F inhibitor approved for the treatment of psoriasis

The fully humanized monoclonal antibody bimekizumab can strongly and specifically neutralize IL-17A and IL-17F
.

IL-17A plays a key role in the pathogenesis of plaque psoriasis, psoriatic arthritis and ankylosing spondylitis

▲Schematic diagram of the working mechanism of Bimekizumab (picture source: reference [2])

This approval was supported by three phase 3 clinical trials BE VIVID, BE READY and BE SURE, involving 1,480 patients with moderate to severe psoriasis
.

All studies reached the common primary endpoint and critical secondary endpoint of the trial

(The original text has been deleted)

Reference materials:

[1] UCB Announces European Commission Approval of BIMZELX[®]▼ (bimekizumab) for the Treatment of Adults with Moderate to Severe Plaque Psoriasis.

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