The expression of genetically modified cotton that blocks the synthesis of cotton bellworm hormone dsRNA has been successfully cultivated.

Plant host-mediated RNAi technology has great potential for the control of plant fins and scaly fin pests.
using host plants to express the target gene dsRNA, highly expressed dsRNAs can be ingested into the body by plant-eating insects, and then induce a system RNAi response, which in turn successfully interferes with the expression of the target insect target gene for insecticidal purposes.
the ideal RNAi target gene and apply it to plant insect-resistant breeding is the key issue at present.
zhu Wei research team of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, through the screening of a large number of RNAi targets, finally determined the key base for controlling the metabolism of insect child-keeping hormones because of the best targets.
in cooperation with Zhang Innocent Laboratory of Nanjing Agricultural University, has cultivated genetically modified cotton that can express dsRNA that blocks the synthesis of cotton bellworm hormone, which shows strong insect resistance, especially for Bt-resistant cotton bellworms.
results showed that genetically modified cotton successfully expressed a high amount of dsRNA, the target gene expression in the subject insect was significantly reduced, and the synthesis of the child protection hormone itself was significantly inhibited.
effect of genetically modified cotton polymerization of RNAi and Bt was further enhanced.
, analysis of multi-year insect resistance data show that RNAi insect resistance cotton can significantly delay the production of cotton bellworm resistance.
The polymerized cotton of insect-protecting hormone RNAi and RNAi-Bt can overcome the problem of cotton bellworm's resistance to a single strategy of genetically modified cotton, and lay the foundation for the research and development of the next generation of insect-resistant crops.
the study, published in the Journal of Plant Biotechnology (DOI:10.1111/pbi.12709), was co-authored by Zhu Wei, a researcher at the Institute of Genetic Development, Zhang Innocent, a professor at Nanjing Agricultural University's School of Agriculture, and Bruce E. Tabashnik, a professor in the Department of Insects at the University of Arizona.
also participated in the research work of the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences Xu Guowang team, Nanjing Agricultural University Wu Yidong, Yang Yihua research group.
research has been funded by major projects such as the "863" program.
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