The cover article of the Plant Protein Team of the Institute of Agricultural Products Processing, Chinese Academy of Agricultural Sciences reveals the molecular mechanism of the sleep-promoting effect of peanut stem and leaf extract

China is a big country producing peanuts, with more than 1 million tons of stems and leaves (dry weight) produced every year, and its comprehensive utilization has attracted much attention
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Peanut stems and leaves have a history as a traditional herbal medicine and special food.

Recently, the plant protein structure and function innovation team of the Institute of Agricultural Products Processing, Chinese Academy of Agricultural Sciences published a cover article (Back Cover) "Flavonoid-Like Components of Peanut Stem and Leaf Extract Promote Sleep by" in the international journal Molecular Nutrition & Food Research (IF: 5.
82) Decreasing Neuronal Excitability", systematically revealed the molecular mechanism of peanut stem and leaf extract regulating mice's natural sleep
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Researcher Wang Qiang and Professor Zhang Chen of Capital Medical University are the co-corresponding authors.

This study revealed the peanut stems through the "phenotype to gene" research strategy system such as animal electroencephalogram monitoring (EEG), cell electrophysiology (Cell Patch Clamp), transcriptome analysis (RNA-seq) and molecular simulation (Molecular Docking) The molecular mechanism of leaf extract regulating natural sleep in mice
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The study found that: 7 or 14 days of PSL intragastric intervention (500 mg/kg BW), the total sleep time, slow wave sleep time and rapid eye movement sleep time of male BALB/c mice aged 6 to 8 weeks were obtained Significantly improved

Second-level researcher/doctoral supervisorDeputy Director, Institute of Agricultural Products Processing, Chinese Academy of Agricultural SciencesMember of Central Agriculture and Forestry Committee of Jiu San SocietyNational outstanding scientific and technological workers, the first batch of outstanding agricultural scientific research talents in the country, and advanced individuals in the country’s scientific and technological assistance in precision poverty alleviation.
He was selected into the national "Hundreds and Thousands of Talents Project" and was awarded the honorary title of "Young and Middle-aged Experts with Outstanding Contributions".
He enjoys special allowances from the State Council.
Agriculture Chief of the Innovation Team of "Grain and Oil Processing Technology and Engineering" of the Ministry of Agriculture, Leading Talents of Chinese Academy of Agricultural Sciences, Leading Talents of Taishan, Shandong Province, Chairman of Peanut Food Branch of Chinese Cereals and Oils Association, Vice Chairman of Functional Food Branch of Chinese Food Society, "National Peanut Industry Technology System" Director of Processing Research Office, editorial board member of "NPJ Science of Food", editor-in-chief of food column of "Journal of Integrative Agriculture", guest editor of "Foods"

Has long been engaged in research on the formation mechanism of nerve synapses
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Presided over more than 10 national research projects, including the chief scientist of the National Key R&D Program (2017), the National Funding Committee "Outstanding Youth" Fund (2020), and the National Funding Committee "Outstanding Youth" Fund (2012); selected as National Ten Thousands of Talents Engineering (2019), and led the School of Basic Medical Sciences of Capital Medical University to win the title of "2019 National Education System Advanced Group"

Deng LeiPhD student
Deng Lei, a 2017 master's degree graduate from the Institute of Agricultural Products Processing, Chinese Academy of Agricultural Sciences, is currently studying for a PhD at Wageningen University in the Netherlands
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The main research direction is human nutrition and health
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At present, he has published 7 academic papers in journals such as Molecular Metabolism , Life Science Alliance , Molecular Nutrition & Food Research , Journal of Mass Spectrometry, etc.
, applied for 2 national invention patents, participated in the compilation of 2 books, and participated in the national key research and development plan special project, the national 3 projects including agricultural innovation projects, and participated in the research and development of new products such as sleep-promoting Huaan granules
.