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The clinical trial application of ASC40 combined with bevacizumab in the treatment of patients with recurrent glioblastoma was accepted by the State Food and Drug Administration

 Last Update: 2021-07-06
 Source: Internet
 Author: User

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Gale Pharmaceuticals Co.
, Ltd.
announced today that after communicating with the National Medical Products Administration (NMPA), the clinical trial application of ASC40 combined with bevacizumab for the treatment of patients with recurrent glioblastoma (rGBM) has been accepted
.

It has been reported that lipid metabolism plays a key role in a variety of tumors
.

Fatty acid synthase (FASN) is one of the most important proteins that regulate lipid metabolism

ASC40 (foreign code name TVB-2640) is a potent and safe oral small molecule inhibitor of selective fatty acid synthase
.

The Phase II clinical trial of ASC40 (TVB-2640) combined with bevacizumab in the treatment of patients with first recurrence of high-grade astrocytoma, i.

Dr.
Wu Jinzi, Founder, Chairman and CEO of Gale, said: "This is a key step for the company in the field of tumor pipelines since the announcement of tumor lipid metabolism and oral checkpoint inhibitor R&D investment upgrade on March 30 this year.

.

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