The centralized procurement of injections is speeding up, and how much pressure is there for the provincial alliance and national procurement to cut prices?

On April 27, the Heilongjiang Provincial Drug Centralized Procurement Network issued the "Announcement of the "Eight Provinces and Two Districts" Medical Security Bureau on the Implementation of the Inter-provincial Union Drug Centralized Procurement Work".
The "Eight Provinces and Two Districts" Alliance led by Heilongjiang led the way.
The purchased varieties have officially surfaced, unless the two drugs of lodipine and calcitriol are oral regular-release dosage forms, and the 19 drugs, including tropisetron, cefotiam, and tranexamic acid, are all injections
.

On the evening of the same day, the drug procurement management platform of Xinjiang medical institutions also issued the "Documents for Centralized and Volume Procurement of Drugs from the "2+N" Alliance of Xinjiang Production and Construction Corps of Xinjiang Uygur Autonomous Region", which means that the "2+N" Alliance of Xinjiang Uygur Autonomous Region and Xinjiang Production and Construction Corps initiated the "2 The +N" alliance has officially kicked off
.

It is worth noting that the central procurement focus of the alliance is also tilting towards the field of injections.

Under the top-level design of the normalization and institutionalization of drug procurement by volume, local centralized procurement has ushered in an overall acceleration
.

In a limited view of the volume purchases carried out by the provincial alliances this year, a large variety of injections that have not yet been reviewed by pharmaceutical companies have been newly promoted to the center of the price reduction whirlpool

Less than 50 varieties

"Eight provinces and two districts" alliance collects or launches two rounds

The "Eight Provinces and Two Districts" alliance is jointly carried out by Heilongjiang Province, Shanxi Province, Inner Mongolia Autonomous Region, Liaoning Province, Jilin Province, Hainan Province, Sichuan Province, Guizhou Province, Tibet Autonomous Region, and Qinghai Province.
The number of participating provinces is currently It is second only to the inter-provincial alliance composed of 11 provinces (autonomous regions and corps) including Shaanxi
.

From the perspective of the included varieties, according to the combing, there are 9 varieties of felodipine, torasemide, fluorouracil, ozagrel sodium, iron sucrose injection, lidocaine, calcitriol, tranexamic acid, and argatroban It is the first time to participate in provincial-level mass procurement, or it is expected to refresh the national lowest price of corresponding drugs

  

  According to data from Minai.
com, Argatroban injection, as an anticoagulant drug in the cardiovascular field, has a terminal sales of more than 500 million yuan in public medical institutions in China in 2019, and the growth rate has exceeded 15% in recent years
.

As a classic hemostatic drug, tranexamic acid is currently an indispensable perioperative drug in artificial joint replacement with large surgical trauma.

  

  However, the two major varieties of calcitriol and argatroban have previously appeared in the Guangxi GPO procurement catalog, and repeated products may not attract the provinces to follow
.

What needs to be reminded is that, according to the policy arrangement, the quantity purchased by each province this year may not be less than 50, and the number of varieties purchased by the "eight provinces and two districts" this time is only barely more than half.

    

Innovative recruitment rules

Can the "2+N" alliance become a template everywhere?

  

  The "2+N" alliance initiated by the Xinjiang Uygur Autonomous Region and the Xinjiang Production and Construction Corps is to unite medical institutions in Shaanxi, Gansu, Qinghai, Ningxia, Guangxi and other provinces (regions) to jointly carry out centralized drug procurement
.

In terms of procurement varieties, the "2+N" alliance has confirmed the news circulated in the industry before, expanding the scale of centralized procurement to 60 drugs, which is second to none among the inter-provincial alliances that have published catalogs, and the most eye-catching among them is as many as 30 varieties of injections

  

  From the perspective of the specific varieties of injections, the antibiotics that have not yet been reviewed have almost been exhausted, including amoxicillin sodium and clavulanate potassium, lamoxef sodium, cefmetazole sodium, cefoperazone sodium and sulbactam sodium, and cefotaxime sodium.
Cefoxitin sodium is injected into 6 major varieties
.

The sales scale of systemic antibacterial drugs in 2018 rose to 158.

  

  Unlike other alliances, which have similar recruitment rules, the "2+N" alliance has made many innovations
.

In addition to negotiating and bargaining for the exclusive shortlisted companies to determine the eligibility for selection, to prevent the impact of the competition pattern from affecting the decline, the "2+N" alliance proposes to follow the "integrated drug procurement and comprehensive procurement" for the evaluation team of 3 or more shortlisted companies.

    

National mining and local alliance

Injections welcome the tide of overall price cuts

  

  The industry generally believes that the volume purchase policy has a far greater impact on the injection product market than oral preparations.
This is because injection products can only rely on the in-hospital market, and companies cannot maintain the original sales scale by expanding the out-of-hospital market, and the willingness and extent of price reductions Both will be more obvious, as can be seen from the fierce battles between national mining and provincial-level mining
.

  

  At the beginning of February this year, the Procurement Office of the Inter-provincial Union of "Six Provinces and Two Districts" announced the results of the selection of centralized drug procurement
.
The average price of the 11 selected drugs dropped by 58.
05%, and the largest decrease was 91.
69%.
The prices of many selected injections fell to the floor price, and some injections fell to more than 1 cent per bottle
.
In the same month, the Wuhan Joint Procurement Office for Pharmaceuticals and Equipment announced the results of the first batch of centralized drug procurement in Hubei Province.
All 29 injections were successfully purchased, and a total of 113 drugs were selected
.
According to the Changjiang Daily report, compared with the lowest online price in the country, the highest price drop of the selected price was 85.
38%, and compared with the price of Hubei Province, the highest price drop of the selected price reached 96.
24%
.
From the perspective of the industry, the volume procurement led by the two major alliances may once again set off a wave of price cuts for injections
.

  

  In addition to the provincial-level mass procurement, with the formal implementation of the consistency evaluation policy, the expansion of the centralized procurement of injections has a realistic basis, and more varieties of over-evaluated injections are included in the scope of the national centralized procurement
.
In the fourth batch of national collections, it includes ambroxol injection, propofol medium/long-chain fat emulsion injection, ibuprofen injection, doxofylline injection, parecoxib for injection, and injection Eight varieties including pantoprazole, bortezomib for injection, and bivalerudin for injection were included.
The bidding of participating companies was fierce, and the final selected prices plunged, with an average price reduction of 75%
.

  

  Today, the fifth batch of national medical institutions is in full swing.
Among the 60 varieties, 31 are injections, azithromycin injection, cisatracurium besilate injection, iohexol injection, iodixanol injection, fluconazole Sodium chloride injections, fasudil injections, glycopyrrolate injections, cefuroxime injections and many other common clinical varieties are all listed
.
It , the original research pharmaceutical companies Pfizer, Sanofi, Novartis, GSK and so have two or more injections in the column, the fierce price competition with Henry, Qilu, Yangzi, Cologne and other heads of local pharmaceutical companies
.