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    Home > Active Ingredient News > Drugs Articles > The causes and treatment methods of the failure of the four-ring lyophilization experimental lyophilizer

    The causes and treatment methods of the failure of the four-ring lyophilization experimental lyophilizer

    • Last Update: 2022-09-15
    • Source: Internet
    • Author: User
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    Four-ring lyophilization experimental lyophilizer is mainly used in food, pharmaceutical, biological products and other fields
    .

    The principle is to pre-freeze the moisture in the material (solid), and then sublimate the frozen water in the material in a vacuum environment to obtain the dried material (liquid becomes solid into a gaseous state).

    The shape, color and taste are basically unchanged, and the nutrients and active ingredients of the product are kept to a large extent without loss or destruction
    .

    Four-ring lyophilization experimental lyophilization opportunity failure and solution method fault 1: pressure drop increase treatment method: 1, check whether the pipeline system is blocked; 2.
    Check whether the air treatment capacity is worth the value; 3.
    Check whether the automatic drain valve is leaking; 4.
    Check whether the configured filter is blocked or leaking; 5.
    Check whether the system valve is in the correct position; 6.
    Check whether the output pressure of the air compressor is normal
    .

    Fault two: the treatment method of poor water removal effect: 1, check whether the character drainage device is drained normally; 2.
    Check whether the air treatment capacity is worth the value; 3.
    Check whether the intake air temperature is beyond the limit; 4.
    Check whether the bypass gas that has not been treated by the refrigeration dryer has entered the downstream pipeline; 5.
    Check whether the repair bypass valve is closed tightly; 6.
    Check whether the parameters of the refrigeration system are accurate and whether the refrigerant leaks; 7.
    Check whether the ambient temperature is too high and whether there are any obstacles in front of the air condenser; 8.
    Check whether the cooling water temperature and water volume are normal
    .

    Fault three: abnormal operation causes and treatment methods: 1, the causes of refrigerant high-pressure tripping are: a.
    the ambient temperature is too high b.
    poor ventilation c.
    insufficient cooling water flow or high inlet water temperature d.
    fan failure e.
    high pressure trip switch setpoint is inaccurate f.
    the high-pressure side of the refrigerant system is blocked g.
    The refrigeration system is faulty or improperly adjusted h.
    The cooling surface of the air condenser is covered with
    swag.

    2, the cause of the compressor overcurrent trip: a.
    the power supply voltage is too low b.
    the load is too large c.
    the overcurrent relay or thermal element is set improperly d.
    the oil pressure relay is faulty or improperly
    adjusted.

    3.
    The load is too small or the idle rotation for a long time will cause the low pressure of the refrigerant to be too low, resulting in the tripping of the low pressure protection
    .

    Fault four: the cause of the pressure dew point is too high and the treatment method: 1, the inlet temperature is too high or the air treatment amount is too large; 2.
    The refrigeration system fails, the compressor is not running, and the control valve is set incorrectly or damaged; 3.
    The automatic drainage is not drained smoothly; 4.
    Poor performance of the pre-filter
    .

      
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