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▎The editor of WuXi AppTec's content team "The Lancet-Psychiatry" recently published a study highlighting the impact of the new coronavirus on brain health.
A study of more than 236,000 COVID-19 patients showed that nearly one-third of the patients were diagnosed with a neurological or mental illness within six months of the infection.
Among them, anxiety disorders (17%) and mood disorders (14%) are the most common; among critically ill patients, neurological diseases are not uncommon.
Nearly 7% have strokes and nearly 2% have been diagnosed with dementia.
"This is real-world data collected from a large number of patients, which confirms that the diagnosis rate of mental illness after the new crown is high, and it can also cause serious diseases that affect the nervous system (such as stroke and dementia).
" The corresponding author of the study, University of Oxford, UK ( University of Oxford) Professor Paul Harrison said, “Although the individual risks of most diseases are small, considering the scale of the epidemic and the chronic and long-term effects of many diseases, the impact of these risks at the entire population level is huge.
Medical care The system needs to have sufficient resources to meet the corresponding medical needs.
" Screenshot source: The Lancet Respiratory Medicine Since the new crown pandemic, the medical community has been paying attention to the neurological disease risk of survivors, but there is still a lack of large-scale and long-term data to support this.
.
This retrospective study analyzed the electronic health records of 236,379 COVID-19 patients in the United States, and analyzed the diagnosis of 14 neurological and mental diseases.
These patients are all over 10 years old, infected with the new crown on or after January 20, 2020, and are still alive on December 13, 2020.
Overall, the incidence of neurological or psychiatric diseases diagnosed after the new crown infection is estimated to be 33.
62%, of which 12.
84% are diagnosed with neurological or psychiatric diseases for the first time.The most common diagnoses are anxiety disorder (17%), mood disorder (14%), substance abuse disorder (7%) and insomnia (5%).
The incidence of neurological diseases is low, including intracranial hemorrhage (0.
6%), ischemic stroke (2.
1%) and dementia (0.
7%).
Among patients with severe neo-coronary disease, neurological or mental illnesses are more common, hospitalized patients and severely ill patients The overall diagnosis rate of custodial patients was 38% and 46%, respectively.
Among patients with delirium, the diagnosis rate was as high as 62%.
For specific diseases: intracranial hemorrhage occurred in 2.
7% and 3.
6% of patients in intensive care and delirium, respectively (the proportion of non-hospitalized patients was 0.
3%); the incidence of ischemic stroke was 6.
9% and 9.
4, respectively % (1.
3% of those who were not hospitalized); 1.
7% and 4.
7% were diagnosed with dementia (0.
4% of those who were not hospitalized); 2.
8% and 7% were diagnosed with mental disorders (0.
9% of those who were not hospitalized) .
Image source: 123RF In addition, the research team also compared the data of 1,05579 patients diagnosed with influenza and 236038 patients diagnosed with any respiratory infection (including influenza) during the same period.
Taking into account basic health characteristics such as age, gender, ethnicity, and underlying diseases, the risk of neurological and mental illness diagnosed in patients with new crown infection is 44% higher than that of influenza patients and 16% higher than that of patients with respiratory tract infections.
This means that compared with other influenza and respiratory diseases, the new crown infection does bring a higher risk of neurological and mental diseases.
The first author of the study, Dr.
Max Taquet from the University of Oxford, pointed out: “We now need to observe the longer-term (six months later) health of people infected with the new crown.
This study also suggests that more research is needed to identify neuropsychiatric diseases caused by the new crown infection.
The
research team also admits that the research has its limitations.
For example, the completeness and accuracy of electronic medical records are not yet clear; secondly, many patients with mild illness or asymptomatic infection may not go to the hospital for treatment.
Therefore, there is a lack of relevant data, and the overall condition of the infected persons included in the study may be more serious than that of the general population; in addition, the severity and course of neurological and mental diseases are also lacking in-depth information. In a review article published in the same period, Dr.
Jonathan Rogers of University College London (UCL) pointed out that “because these diseases are often chronic or recurrent, we can expect that the impact of the new crown may last for several years.
” Related reports on the new crown study : "The Lancet": Six months after Jinyintan Covid-19 patients were discharged from the hospital, 76% still have symptoms "This virus is unusual".
.
.
"Nature-Medical" summarizes the new coronavirus's attack on nearly 10 organ systems other than the lung, released by the British Institute of Health Report on long-term symptoms and effects of new crown: patients may face four syndromes.
After patients with new crown are discharged from hospital and the nucleic acid turns negative, which symptoms are still continuing? JAMA published Italian data reference materials[1] Maxime Taquet, et al.
, (2021).
6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records.
The Lancet Psychiatry, DOI : https://doi.
org/10.
1016/S2215-0366(21)00084-5[2] The Lancet Psychiatry: Largest study to date suggests link between COVID-19 infection and subsequent mental health and neurological conditions.
Retrieved Apr 7, 2021, from Note: This article aims to introduce the progress of medical and health research, not a treatment plan recommendation.
If you need guidance on treatment plans, please go to a regular hospital for treatment.
A study of more than 236,000 COVID-19 patients showed that nearly one-third of the patients were diagnosed with a neurological or mental illness within six months of the infection.
Among them, anxiety disorders (17%) and mood disorders (14%) are the most common; among critically ill patients, neurological diseases are not uncommon.
Nearly 7% have strokes and nearly 2% have been diagnosed with dementia.
"This is real-world data collected from a large number of patients, which confirms that the diagnosis rate of mental illness after the new crown is high, and it can also cause serious diseases that affect the nervous system (such as stroke and dementia).
" The corresponding author of the study, University of Oxford, UK ( University of Oxford) Professor Paul Harrison said, “Although the individual risks of most diseases are small, considering the scale of the epidemic and the chronic and long-term effects of many diseases, the impact of these risks at the entire population level is huge.
Medical care The system needs to have sufficient resources to meet the corresponding medical needs.
" Screenshot source: The Lancet Respiratory Medicine Since the new crown pandemic, the medical community has been paying attention to the neurological disease risk of survivors, but there is still a lack of large-scale and long-term data to support this.
.
This retrospective study analyzed the electronic health records of 236,379 COVID-19 patients in the United States, and analyzed the diagnosis of 14 neurological and mental diseases.
These patients are all over 10 years old, infected with the new crown on or after January 20, 2020, and are still alive on December 13, 2020.
Overall, the incidence of neurological or psychiatric diseases diagnosed after the new crown infection is estimated to be 33.
62%, of which 12.
84% are diagnosed with neurological or psychiatric diseases for the first time.The most common diagnoses are anxiety disorder (17%), mood disorder (14%), substance abuse disorder (7%) and insomnia (5%).
The incidence of neurological diseases is low, including intracranial hemorrhage (0.
6%), ischemic stroke (2.
1%) and dementia (0.
7%).
Among patients with severe neo-coronary disease, neurological or mental illnesses are more common, hospitalized patients and severely ill patients The overall diagnosis rate of custodial patients was 38% and 46%, respectively.
Among patients with delirium, the diagnosis rate was as high as 62%.
For specific diseases: intracranial hemorrhage occurred in 2.
7% and 3.
6% of patients in intensive care and delirium, respectively (the proportion of non-hospitalized patients was 0.
3%); the incidence of ischemic stroke was 6.
9% and 9.
4, respectively % (1.
3% of those who were not hospitalized); 1.
7% and 4.
7% were diagnosed with dementia (0.
4% of those who were not hospitalized); 2.
8% and 7% were diagnosed with mental disorders (0.
9% of those who were not hospitalized) .
Image source: 123RF In addition, the research team also compared the data of 1,05579 patients diagnosed with influenza and 236038 patients diagnosed with any respiratory infection (including influenza) during the same period.
Taking into account basic health characteristics such as age, gender, ethnicity, and underlying diseases, the risk of neurological and mental illness diagnosed in patients with new crown infection is 44% higher than that of influenza patients and 16% higher than that of patients with respiratory tract infections.
This means that compared with other influenza and respiratory diseases, the new crown infection does bring a higher risk of neurological and mental diseases.
The first author of the study, Dr.
Max Taquet from the University of Oxford, pointed out: “We now need to observe the longer-term (six months later) health of people infected with the new crown.
This study also suggests that more research is needed to identify neuropsychiatric diseases caused by the new crown infection.
The
research team also admits that the research has its limitations.
For example, the completeness and accuracy of electronic medical records are not yet clear; secondly, many patients with mild illness or asymptomatic infection may not go to the hospital for treatment.
Therefore, there is a lack of relevant data, and the overall condition of the infected persons included in the study may be more serious than that of the general population; in addition, the severity and course of neurological and mental diseases are also lacking in-depth information. In a review article published in the same period, Dr.
Jonathan Rogers of University College London (UCL) pointed out that “because these diseases are often chronic or recurrent, we can expect that the impact of the new crown may last for several years.
” Related reports on the new crown study : "The Lancet": Six months after Jinyintan Covid-19 patients were discharged from the hospital, 76% still have symptoms "This virus is unusual".
.
.
"Nature-Medical" summarizes the new coronavirus's attack on nearly 10 organ systems other than the lung, released by the British Institute of Health Report on long-term symptoms and effects of new crown: patients may face four syndromes.
After patients with new crown are discharged from hospital and the nucleic acid turns negative, which symptoms are still continuing? JAMA published Italian data reference materials[1] Maxime Taquet, et al.
, (2021).
6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records.
The Lancet Psychiatry, DOI : https://doi.
org/10.
1016/S2215-0366(21)00084-5[2] The Lancet Psychiatry: Largest study to date suggests link between COVID-19 infection and subsequent mental health and neurological conditions.
Retrieved Apr 7, 2021, from Note: This article aims to introduce the progress of medical and health research, not a treatment plan recommendation.
If you need guidance on treatment plans, please go to a regular hospital for treatment.
