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Uridine(5')tetraphospho(5')uridine tetrasodium salt, also known as PEG-uridine or UTP, is a synthetic nucleoside that has a wide range of applications in the chemical industry.
Uridine is a natural nucleoside that is found in all living organisms, and it plays an important role in the synthesis of RNA and DNA.
UTP is a modified form of uridine that has been chemically modified to make it more stable and to improve its solubility in water.
One of the most important applications of UTP is in the field of molecular biology, where it is used as a starting material for the synthesis of oligonucleotides.
Oligonucleotides are short sequences of nucleotides that are used as probes to detect specific sequences of DNA or RNA.
They are also used as primers for PCR, and as tools for studying gene expression and regulation.
UTP can be polymerized using enzymatic or chemical methods to form oligonucleotides of varying lengths and sequences.
UTP is also used as a substrate for the synthesis of short interfering RNA (siRNA) and microRNA (miRNA).
SiRNA and miRNA are small RNAs that play important roles in gene regulation by interfering with the translation of specific mRNAs.
They are used as tools to study gene function and to develop therapeutics for a variety of diseases.
UTP can be chemically modified to introduce specific sequences and structures that are required for the efficient synthesis and stability of siRNA and miRNA.
In addition to its use in molecular biology, UTP has a number of other applications in the chemical industry.
It is used as a phosphorylation agent for the synthesis of phosphate-labeled nucleotides and proteins.
This is useful for studying the metabolism and localization of these molecules in cells and for detecting specific protein-DNA interactions.
UTP is also a powerful tool for the synthesis of modified RNA and DNA molecules.
It can be used as a substrate for the addition of specific modifications, such as fluorescent dyes or biotin, that are useful for studying the structure and function of RNA and DNA in cells.
These modified molecules can also be used as probes or primers for a variety of applications in molecular biology.
Finally, UTP has been used as a component of gene therapy vectors.
Gene therapy is a rapidly growing field that involves the introduction of functional genes into cells to treat diseases.
UTP has been used as a component of viral vectors that are used to deliver genes into cells.
These vectors are engineered to contain the necessary elements for efficient gene transfer, including promoter sequences, enhancer elements, and translation signals.
In conclusion, uridine(5')tetraphospho(5')uridine tetrasodium salt is a versatile molecule that has a wide range of applications in the chemical industry.
Its stability and solubility make it an ideal starting material for the synthesis of oligonucleotides, and its ability to be chemically modified makes it a powerful tool for the synthesis of modified nucleotides and proteins.
It is also used in the synthesis of siRNA and miRNA, and as a component of gene therapy vectors.
Its applications in molecular biology, biotechnology and pharmaceutical industry are growing day by day.