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IMIDAZO[1,5-A]PYRIDINE-1-CARBOXYLIC ACID ETHYL ESTER, also known as IMAC, is a widely used ligand in the chemical industry.
It has a variety of applications in different fields, including catalysts, medicinal chemistry, and materials science.
One of the most common use of IMAC is in catalytic asymmetric synthesis.
This process involves the use of chiral catalysts to produce enantiopure compounds, which can be used as building blocks for the synthesis of drugs, agrochemicals, and other chemical products.
IMAC is a versatile ligand that can bind to various metal ions, such as ruthenium, osmium, and iridium, to form chiral catalysts.
These catalysts can be used in a variety of reactions, including aldol, aldol-like, and Michael additions.
Another application of IMAC is in the area of medicinal chemistry.
It is a common ligand in the design of drugs that target various protein kinases, such as tyrosine kinases.
In this field, IMAC is used as a phosphorylating agent, which can be used to modify proteins and study their activity.
IMAC derivatives can also be used as inhibitors of protein kinases, which can be used to treat various diseases, such as cancer and inflammatory disorders.
IMAC is also used in materials science, particularly in the field of supramolecular chemistry.
In this area, IMAC is used as a building block for the formation of supramolecular assemblies, such as molecular switches and sensors.
These assemblies can be used in a variety of applications, including catalysis, nanotechnology, and electronics.
In addition to the above-mentioned applications, IMAC is also used in the field of bioconjugation.
This process involves the covalent attachment of IMAC to various biomolecules, such as antibodies, peptides, and oligonucleotides.
This can be used to improve the selectivity and efficacy of drugs, as well as to label biomolecules for various imaging techniques.
In conclusion, IMIDAZO[1,5-A]PYRIDINE-1-CARBOXYLIC ACID ETHYL ESTER is a versatile ligand that has a variety of applications in the chemical industry.
Whether it is in catalytic asymmetric synthesis, medicinal chemistry, materials science, or bioconjugation, IMAC is a valuable tool that can be used to produce a wide range of chemical compounds and products.