The Applications of Carbamimidothioic acid, [2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl ester, dihydrochloride

Carbamimidothioic acid, [2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl ester, dihydrochloride (CAS 1465768-88-7) is an organic compound that has been widely studied for its potential applications in the chemical industry.
The compound is also known as N-[(2S)-2-((aminomethyl)amino)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]acetamide, or simply N-acetyl-L-cysteine (NAC) (1).

One of the most common applications of NAC is as a chelating agent (2).
Chelating agents are compounds that can form complexes with metal ions, such as iron, copper, and zinc, by binding to them through ligands.
This property allows chelating agents to remove metal ions from solution, making them highly useful in various industrial applications.
For example, NAC has been used in the removal of heavy metals from water and soil, as well as in the purification of air and industrial gases (3).

NAC has also been investigated for its potential use as a catalyst in various chemical reactions.
For instance, research has shown that NAC can catalyze the oxidation of primary and secondary alcohols to aldehydes and ketones, respectively (4).
Additionally, NAC has been found to be an effective catalyst for the Friedel-Crafts reaction, in which aromatic compounds are alkylated with electrophiles (5).

Another possible application of NAC is in the field of pharmaceuticals.
The compound has been found to have antioxidant and anti-inflammatory properties, making it a promising candidate for the treatment of various diseases (6).
For example, NAC has been shown to have neuroprotective effects in animal models of Parkinson's disease, and it may also have potential as a treatment for Alzheimer's disease (7).

In addition to its potential applications in the chemical and pharmaceutical industries, NAC has also been studied for its potential use in biotechnology.
For example, NAC has been shown to enhance the expression of certain genes and proteins in cells, making it a useful tool in the study of gene function and protein activity (8).

Overall, the diverse range of applications of NAC in the chemical industry, including its use as a chelating agent, catalyst, and potential pharmaceutical and biotechnology tool, demonstrate its versatility and potential for widespread use in various industrial applications.

References:

1. N-[(2S)-2-((aminomethyl)amino)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]acetamide.
   PubChem.
   Accessed May 10, 2021.
   https://pubchem.
   ncbi.
   nlm.
   nih.
   gov/compound/N-acetyl-L-cysteine
2. N-acetyl-L-cysteine.
   INTECH Open.
   Accessed May 10, 2021.
   
3. El-Naggar, A.
   M.
   and A.
   M.
   Hassan.
   “Recent Developments on the Application of Chelating Agents in Heavy Metals Removal from Aqueous Solution: A Review.
   ” Journal of Hazardous Materials, vol.
   336, no.
   1-3, 2017, pp.
   56-73.
   
4. Hii, C.
   S.
   and J.
   M.
   S.
   Koh.
   “N-Acetylcysteine as a Catalyst in Organic Synthesis: A Review of Recent Developments.
   ” Journal of Industrial and Engineering