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(1S,3S)-1-Ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid, also known as sonidegib, is a selective smoothened inhibitor used in the treatment of various types of cancer, especially those of the ovaries, lung, and gastrointestinal tract.
This compound has also been found to possess antiproliferative and anti-inflammatory properties, making it a promising drug for cancer treatment.
In addition to its potential use in cancer treatment, (1S,3S)-1-ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid has several other applications in the chemical industry.
Some of these applications include:
- As a building block for the synthesis of other pharmaceuticals: The structural features of (1S,3S)-1-ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid make it a useful building block for the synthesis of other pharmaceuticals.
Its biological activity and chemical properties can be exploited to create new drugs with improved efficacy and safety profiles. - As a cosmetic ingredient: (1S,3S)-1-ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid has been found to possess antioxidant and anti-inflammatory properties, making it a potentially useful ingredient in cosmetic products.
These properties may help to protect the skin from damage caused by environmental stressors such as UV radiation and pollution. - As a flavoring agent: The distinctive aroma and taste of (1S,3S)-1-ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid have led to its use as a flavoring agent in certain food products.
Its unique odor is often described as earthy or woody, making it a useful ingredient in natural and organic foods. - As a biodegradable plasticizer: (1S,3S)-1-ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid has been found to have plasticizing properties, making it a potential ingredient in biodegradable plastics.
These plastics can degrade over time, leaving no harmful residues behind, making them an environmentally-friendly alternative to traditional plastics.
In conclusion, (1S,3S)-1-ethyl-2,3,4,9-tetrahydropyrano[3,4-b]indole-3-carboxylic acid has a wide range of applications in the chemical industry beyond its potential use in cancer treatment.
Its unique properties make it a versatile building block for the synthesis of other compounds and a potentially useful ingredient in cosmetics, flavorings, and biodegradable plastics.