The African swine fever vaccine was created successfully

1, the English-language edition of China Science: Life Sciences published the latest research results of the National African Swine Fever Professional Laboratory of Harbin Veterinary Research Institute of the Chinese Academy of Agricultural Sciences online. The laboratory has created a live vaccine for the weak poison of African swine fever. The vaccine has good safety and effectiveness for pigs after systematic laboratory research and evaluation.
-detoxifying live vaccine is considered the most promising research and development strategy for the swine fever vaccine in Africa. Using PigHLJ2018, the first African swine fever virus isolated strain in China, the researchers constructed a series of recombination viruses with different gene deficiencies using hoso-recombination technology. By conducting systematic pathogenic, immunogenic and immunoptopytic tests in pigs, they selected a virus with seven missing genes (HLJ18-7GD) that met the safety standards of the weakly venomed live vaccine and provided effective immune protection against deadly attacks by african swine fever.
, there have been some international reports of african swine fever virus gene deficiency live vaccine. After these vaccinations, pigs have a more serious viralemia, the body continued to be poisoned for a long time, the risk of strong resistance is high.
, HLJ18-7GD does not replicate in real organs even after the maximum dose is given to pigs, and does not produce viralemia. In addition, the vaccine is also good for pregnant sows. The researchers said that the vaccine is by far the most promising industrial application of the vaccine, will be China and the countries concerned to effectively prevent and control the outbreak of swine fever in Africa to provide an important technical means. (Source: Li Chen, China Science Journal)
paper information: ht