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The 2nd paragraph in the country!

 Last Update: 2022-02-25
 Source: Internet
 Author: User

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Article source: Medical Cube Info

On November 29, Junshi Bio announced that the clinical trial application for Aurora A inhibitor WJ05129 tablets (JS112) of Suzhou Junjing Bio (which jointly invested with Weijing Bio) has been accepted by NMPA

Aurora A, a member of the serine/threonine protein kinase in the Aurora kinase family, plays an important role in the process of cell mitosis

JS112 is an oral small-molecule Aurora A inhibitor, which has a synthetic lethal effect with RB1 gene deletion or inactivation, and can be used to treat malignant tumors with RB1 deletion or inactivation such as small cell lung cancer and triple-negative breast cancer

At present, there is no Aurora A inhibitor approved for marketing in the world

Medicine Rubik's Cube NextPharma

In China, in October this year, the clinical application for the Aurora A inhibitor VIC-1911 of Jisi Yingda was accepted by the NMPA

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