The 2022 China Dairy Industry Technology and High-quality Development Symposium - Early Life Nutrition and Health and the 4th Breast Milk Research Summit Forum was held

Reporter Wang Wei

The first 1,000 days of life is not only a window of opportunity for human development, but also a critical period
for nutritional regulation that affects lifelong health.
Improving maternal and infant health is an important part of building a "healthy China", and carrying out research on breast milk and early life nutrition is of special significance
to promoting maternal and infant health.
Recently, the 2022 China Dairy Science and Technology and High-quality Development Symposium - Early Life Nutrition and Health and the 4th Breast Milk Research Summit Forum, hosted by the Chinese Society of Food Science and Technology and supported by Yili Institute of Maternal and Child Nutrition, was held
in Beijing in a combination of offline and online 。 As an annual academic event in the field of human milk research in China, this conference focuses on the latest scientific and technological achievements in human milk research, brings together academicians and experts in the field of food and breast milk research in China, discusses the frontier progress in the field of human milk research, new trends in industrial development, and further promotes the research level and industrial innovation of infant formula milk powder, so as to empower the high-quality development level
of China's dairy industry.

Forum site

Increase collaborative innovation between production, education and research to promote the in-depth development of human milk component research

Professor Meng Suhe, honorary chairman of the Chinese Society of Food Science and Technology, said in his speech that China's food industry has shown resilience to climb up after experiencing low operation, its development model is undergoing profound changes, the intrinsic quality is also improving, and nutrition and health have become the core competitiveness
to enhance product value.
The Breast Milk Research Summit Forum has been held for four consecutive years, and it has still persevered in the context of the epidemic, reflecting the perseverance and technology-oriented values
of the industry and science and technology circles in scientific and technological innovation and basic research fields.
She pointed out that China's dairy industry is poised to develop and has entered a new stage of historical development, and it is necessary to rely on science and technology to persistently build future-oriented soft power, meet the diversified needs of the market, and lead the high-quality development
of China's dairy industry.

"Nutrition is the cornerstone of health, and it is of great significance
to clarify the nutritional needs of infants and young children at different stages of growth and provide them with nutritious and healthy foods.
" Ren Fazheng, academician of the Chinese Academy of Engineering and vice president of the Chinese Society of Food Science and Technology, affirmed the role of human milk and infant nutrition research in his speech, and suggested that more attention should be paid to the research of breast milk and infant nutrition, and further clarify the research on human milk components, and develop healthy products
suitable for infants and young children.

Situ Wenyou, senior scientific research director of Yili Institute of Maternal and Child Nutrition, said in his speech that China's dairy industry is entering the "fast lane" of development, and it is also necessary to promote collaborative innovation between industry, education and research, carry out independent research on Chinese breast milk, and develop formula milk powder
suitable for infant nutrition in China.
This is the only way for the high-quality development of the industry, and it is also an inevitable choice
for building an innovative country.
"Children are not a scaled-down version of adults, but have special nutritional needs
.
" Yili is a dairy enterprise driven by scientific and technological innovation, and it is also one of
the earliest dairy enterprises in China to enter the field of early life nutrition research.
Over the past 20 years, Yili has gathered global resources, promoted collaborative innovation between industry, education and research, and achieved fruitful academic results
.
In the future, Yili will scientifically plan infant and early life nutrition for children, and fully promote the construction of
"Healthy China".

Professor Luo Yunbo, Honorary Vice President of the Chinese Society of Food Science and Technology and Director of the Special Food Research Center of China Agricultural University, and Professor Wang Zhiyi of Nanjing Medical University presided over the meeting
。 Experts and scholars from Peking University, Nankai University, Nanchang University, Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, Northwest A&F University, Institute of Nutrition and Health of the Chinese Center for Disease Control and Prevention, China Agricultural University and other universities and research institutes exchanged views on hot topics such as frontier progress in human milk research, early life nutrition and exercise, human milk oligosaccharides, breast milk lipids, dairy and children's immunity and bone development, and new technologies for infant food manufacturing, and shared
。

Consolidate basic research from the research of breast milk composition to industrial application

Only by consolidating basic research can the industry be
firmly established.
In recent years, domestic experts and scholars have carried out in-depth research on functional components in breast milk such as human milk oligosaccharides and breast milk lipids, and have made certain progress
.
At the meeting, a number of experts carried out in-depth exchanges
on the basic research of the functional components of human milk.

Professor Wang Shuo, Deputy Dean of the Institute of Public Health and Health of Nankai University, pointed out in the report entitled "Frontier Scientific and Technological Progress of Human Milk Oligosaccharides" that human milk oligosaccharides are currently a hot spot
in human milk research.
Human milk oligosaccharides are the third largest solid component in human milk, after lactose and fat, and more than 200 kinds of human milk oligosaccharides
have been isolated from human milk.
Breast milk oligosaccharides have various functions such as regulating the body's immunity and promoting cognition, and can establish contact
with the brain through the gut-brain axis by adjusting the structure of the flora or with the help of bacterial metabolites produced.
Studies carried out in Shanghai, Guangzhou, Tianjin and other places have shown that human milk oligosaccharides account for 40%
of the total content of human milk oligosaccharides.
From the current point of view, microbial fermentation is a more mature way to achieve large-scale production of human milk oligosaccharides, and further clinical research on human milk oligosaccharides and analysis of their health effects
are needed in the future.

Professor Wang Zhiyi from the School of Public Health of Nanjing Medical University shared a report
entitled "Frontier Progress in Breast Milk Research in China".
Wang Zhiyi introduced that at present, China has established an independent human milk research system, and its research strength and research level have reached the international level
.
Wang said that the study found that some breast milk components are affected by the genetics of the population or diet and lifestyle, and there are certain differences
between regions.
In addition, the study compared
human milk in 22 regions in 14 countries.
It was found that the countries surveyed paid more attention to whey protein research but not casein
.
Yili makes full use of the existing research results for product application and transformation, and forms a unique professional solution - α-whey protein and β-casein combined infant formula program
.
In addition, the study identified and differentiated
the protein components of human milk in different countries in a omics manner.

Professor Deng Zeyuan, Deputy Director of the State Key Laboratory of Food Science and Technology of Nanchang University, analyzed the research on human milk lipids and their industrial application
from the perspective of infant formula research and development.
Deng Zeyuan pointed out that among breast milk lipids, OPO structural lipids are the most easily digested and absorbed in the gastrointestinal tract, and there are differences
between OPO structural lipids in Chinese breast milk and foreign countries.
Compared with OPO structural lipids with higher content in foreign breast milk, OPL structural lipids with higher content in Chinese breast milk are easier to absorb and transport
in Caco-2 monolayer cells.
Studies have found that the position isomerization and unsaturation of fatty acids in triglycerides have important effects
on the digestive system of structural lipids.
In the future, in the research and development of infant formula, the emulsification of structured fat of human milk should also pay attention to lipid components
such as phospholipids and cholesterol.

In 2022, the Chinese Society of Food Science and Technology released the "Six Trends in Human Milk and Early Life Nutrition Research"
.
As the main author of this achievement, Professor Guo Huiyuan from the College of Food Science and Nutritional Engineering of China Agricultural University brought a report
entitled "Six Hot Directions of Human Milk Science and Infant Food Manufacturing Technology".
Starting from the analysis of nutritional needs in early life, Guo Huiyuan analyzes the composition of breast milk, and then guides the development of
new functional binders.
The six hot directions of human milk science and infant food manufacturing technology research are: analysis of nutritional requirements in early life, in-depth exploration of human milk components, observation of the health effects of breast milk, innovative creation of functional binders, development of new binder detection technology and evaluation methods, and efficient retention
of bioactive ingredients.
She noted that early life nutrition has a significant impact on the health and disease risk of mother and baby populations, and that the intake of key nutrients is essential
for maintaining early life health.
Guo Huiyuan said that the research on manufacturing technology of breast milk and infant food is of special significance to promote maternal and child health, and is an important measure
to realize the "Healthy China" strategy.
The in-depth analysis of the scientific frontier in the field of breast milk and infant food manufacturing will promote the in-depth development of early life nutrition research and help improve the nutritional health level of
mothers and infants in China.

Broadening research from the early 1,000 days of life to focusing on child development

Duha theory believes that in addition to the "window of opportunity" of 1,000 days in the early part of life, childhood and adolescence are also sensitive stages
of growth and development.
At this stage, a balanced intake of nutrients is essential for children, and their habitual, social and cognitive skills are easier to develop
than in adulthood.
Early childhood nutrition interventions improve children's survival and development and promote healthy growth
.
The participating experts deeply explored the problems and challenges faced in child nutrition research and explored the ways to solve them
.

Yang Zhenyu, a researcher at the Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention, made a report
on "Dairy and Children's Bone Development".
He said that studies have found that protein, calcium, magnesium, vitamin D and vitamin K are important nutrients
that affect bone health in childhood.
The right ratio of these nutrients works synergistically for optimal bone development
in children.
Dairy products are not only an important source of protein, calcium and magnesium, but also as a carrier for vitamin D fortification, and reasonable intake of dairy products can help children's bone development
.

Professor Chen Tongxin, Chief Physician of Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine, introduced children's immune development from the perspective of immunology
.
He pointed out that there are many kinds of bioactive components of breast milk, which can participate in the construction
of immune system from the aspects of directly participating in immune response, promoting intestinal development, improving intestinal mucosal barrier, regulating immune response, and building intestinal microecology.

Professor Yumei Zhang from the School of Public Health of Peking University shared the report on early life nutrition and infant behavior and motor development in China
.
She pointed out that according to the survey of nutrition and health of infants aged 0-36 months in 10 regions of China (referred to as "Yi Research"), the evaluation of screen time for infants aged 0-3 found that compared with WHO guidelines, more than half of children aged 1-2 reported that their daily screen exposure time was too long; The incidence of overlength in children aged 2-3 years is as high as about 69%; About 10%
of infants aged 0-1 years.
At the same time, sleep problems still need attention, the incidence of self-reported sleep deprivation in children aged 1-3 years is about 12%-20%, and the incidence of insufficient sleep in infants aged 0-3 months is about 35%.

In addition, the study analyzed the relationship between
diet and infant and young child health.
The rich α-lactalbumin in breast milk helps sleep, and what is the impact of α-lactalbumin-rich OPO infant formula on infant health? Through parallel control experiments, it was found that the length level of infants in the experimental group was better than that of the control group, similar
to that of the breastfeeding group.

Professor Liu Xuebo, Assistant President of Northwest A&F University, introduced the nutritional
intervention of food functional factors on lipid metabolism and neurodevelopment in early life.
He believes that maternal health affects offspring, and dietary interventions in the mother during a critical window early in life may modify offspring health
.
Studies based on animal models have shown that maternal high-fiber dietary patterns improve the metabolic health of offspring and affect cognitive and social function development
in infants and young children.

Roundtable forum on "Early Life Nutrition and Infant Motor and Behavioral Development"

The organizers of the conference also set up a roundtable forum on
"Early Life Nutrition and Infant Movement and Behavioral Development".
In this session, the participating experts discussed
"Early Life Nutrition and Infant Motor and Behavioral Development".
From the needs of exercise and nutrition in early life, to the functional factors of breast milk, to immunity and bone development, and finally to the development of innovative products, the detailed introduction is systematically and systematically from multiple angles, focusing on the frontier progress and new trends of nutrition and health research in early life in China, which has important guiding significance
for future related research.

The development of China's dairy industry will usher in a period of strategic opportunities to rely on the power of science and technology to continue to climb and rise, the dependence on scientific and technological innovation will deepen, and the demand for the docking of science and technology and industry will increase
unprecedentedly.
Experts attending the meeting said that as a high-level scientific research and exchange platform in the field of mother, infant and child nutrition, the Breast Milk Research Summit Forum will always stand at the forefront of the field, lead the development trend of early life nutrition, and lay a solid foundation
for promoting the high-quality development of China's dairy industry with self-reliance and self-improvement of science and technology.
Xinhua News Agency, Guangming Net, Weibo (Yi Live Broadcast) and other media broadcast the meeting live.

By the end of the seminar, the cumulative number of views on the whole network was nearly 3.
5 million
.

Responsible editor: Zhang Jiazhen Review: Peng Zonglu