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Article source: Pharmaceutical Guanlan
On October 29, The Galien Foundation announced the winners of the 2021 Prix Galien USA Awards
.
The Galen Prize, known as the "Nobel Prize in Medicine," is recognized as the highest honor in the pharmaceutical and biomedical industry.
The Galen Prize is selected by a jury containing multiple Nobel Prize winners.
The awards include Best Biotechnology Product, Best Pharmaceutical Agent, and Best Medical Technology Product.
Technology) and the Best Digital Health Solution (Best Digital Health Solution)
.
They are all products that have been approved by the US FDA in the last 5 years and have the potential to have a significant impact on human health
Picture source: reference [2]
1.
Best Biotechnology Product Award: Oxbryta (voxelotor), Global Blood Therapeutics
Best Biotechnology Product Award: Oxbryta (voxelotor), Global Blood Therapeutics
Oxbryta is the first FDA-approved innovative therapy that targets the hemoglobin polymerization process and represents an innovative mechanism of action for the treatment of sickle cell anemia (SCD)
.
SCD is an inherited blood disease that accompanies the patient's life.
Oxbryta is an innovative treatment for SCD that is taken orally once a day.
It achieves curative effect by increasing the affinity of hemoglobin for oxygen
.
Because oxygenated sickle hemoglobin does not polymerize, Oxbryta can prevent sickle changes in red blood cells and damage to red blood cells
2.
Best Drug Award: Entresto (Sakubatril/Valsartan, Novartis), Novartis
Best Drug Award: Entresto (Sakubatril/Valsartan, Novartis), Novartis
Entresto is Novartis' heavy heart failure drug and the first drug that can simultaneously treat heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF)
.
Prior to this, Entresto has been approved for listing in more than 100 countries around the world
Entresto is formed by the combination of the enkephalinase inhibitor sacubatril and the angiotensin receptor antagonist valsartan.
The combination of the two can better play a beneficial effect
.
On the one hand, sacubitril can enhance the beneficial effects of the natriuretic peptide system, play natriuretic diuresis, relax blood vessels and protect the heart
3.
Best Medical Technology Product Award: AcrySof IQ PanOptix Trifocal Intraocular Lens (IOL), Alcon
Best Medical Technology Product Award: AcrySof IQ PanOptix Trifocal Intraocular Lens (IOL), Alcon
AcrySof IQ PanOptix Trifocal Intraocular Lens (IOL) developed by Alcon is a multifocal intraocular lens used to clearly focus the image on the back of the eye (retina) after cataract removal to make vision clear
.
In addition, compared with a single focal length lens, the center of the AcrySof IQ PanOptix trifocal intraocular lens can provide better near (reading) vision and intermediate (computer work) vision
In August 2019, the product was approved by the FDA for marketing, becoming the first trifocal lens approved for use in patients undergoing cataract surgery
.
Clinical trials have proved that PanOptix can provide a special combination of near, intermediate and long distance vision, while significantly reducing the need for glasses after surgery
4.
Best Digital Health Product Award: Remote Patient Monitoring Platform, Huma Therapeutics
Best Digital Health Product Award: Remote Patient Monitoring Platform, Huma Therapeutics
Founded in 2011, Huma Therapeutics is a digital therapy/digital biomarker development company
.
The company's modular remote patient management platform can provide life science companies with services such as decentralized clinical trials, real-world data collection, and patient support
.
It is reported that the platform combines predictive algorithms, digital biomarkers and real-world data to advance forward-looking medical care and clinical research
.
Huma's remote patient monitoring (RPM) solution aims to support healthcare organizations by providing more care opportunities outside of the traditional environment, and to help patients better manage their health
.
The modular solution can help track disease symptoms and vital signs, as well as mark disease deterioration, and integrate telemedicine functions to integrate with medical devices
.
Note: The original text has been deleted
Reference materials:
[1] Prix Galien Award.
Retrieved October 28, 2021, from https:// The Galien Foundation Honors Excellence in Scientific Innovation at 2021 Prix Galien Awards Gala.
Retrieved Oct 29, 2021, from https:// -scientific-innovation-at-2021-prix-galien-awards-gala-301411801.
html
[3] Novartis Entresto® granted expanded indication in chronic heart failure by FDA.
Retrieved February 16, 2021, from https:// -heart-failure-fda
[4] FDA approves novel treatment to target abnormality in sickle cell disease.
Retrieved November 25, 2019, from https:// in-sickle-cell-disease-300964854.
html
[5] Alcon Introduces AcrySof IQ PanOptix Trifocal IOL in the US, the First and Only FDA-Approved Trifocal Lens.
Retrieved Aug 27, 2019, from https:// -iq-panoptix-trifocal-iol-us-first-and-only-fda-approved
[6]Huma's Remote Patient Monitoring solution.
From https://huma.
com/rpm/us