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    Home > Active Ingredient News > Antitumor Therapy > Targeting HER2 antibody drug conjugateENHERTU for breast cancer, gets quick review by the European Medicines Agency

    Targeting HER2 antibody drug conjugateENHERTU for breast cancer, gets quick review by the European Medicines Agency

    • Last Update: 2020-07-14
    • Source: Internet
    • Author: User
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    Daiichi/AstraZeneca, Inc.,an antibody drug conjugate dating her2 ENHERTU (FAM-traszumab deruxtecan-nxki) for the treatment ofbreast cancerand obtained an accelerated review by the European DrugAdministrationBureau (EMA)The drug was approved by the U.SFood and Drug Administration (
    FDA) in December to treat patients with HER2-positive metastatic breast cancer who have previously received two or more treatments based on the anti-HER2 regimenFDA approval and THE EMA's accelerated review are based on data from the DESTINY-Breast01 trial, which evaluated ENHERTU in patients previously treated with Herceptin, Perjeta, or KadcylaThe results showed that ENHERTU reached an objective mitigation rate of 60%, including more than 4% of total mitigation, and the median mitigation period was 14.8 monthsAZ reached a $6.9 billion cooperation agreement with Daiichi in March last year to commercialize ENHERTUanalysts predict edited that AZ/Daiichi's drug could replace Kadcyla as a multibillion-dollar drug with sales of up to $12 billion
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