Tardigrades also have trisolaran dehydration resurrection skills The key CAHS protein for dehydration resurrection can be expressed in human cells

Water is an important molecule for maintaining the metabolic activity and cellular integrity of organisms

Some tardigrades (also known as tardigrades) can survive in different environments that are not conducive to most life- or even deadly, and although they are very small, their miraculous ability to survive is easy to arouse people's imagination — by deciphering their secrets, we may be able to apply this knowledge to ourselves, making humans more adaptable to extreme temperatures, pressures, and even dehydration – although this is still science fiction

Researchers from the University of Tokyo have described for the first time a new mechanism that explains how some tardigrades endure extreme dehydration without dying

Tardigrades are able to tolerate almost complete dehydration by entering a reversible metabolic state called dehydrated organisms and rejuvenate after rehydration

The authors first hypothesized that some of the tolerant proteins in tardigrades formed reversible protective condensates by phase separation in a stress-dependent manner, and through a comprehensive search of trifluoroethanol (TFE) for decontamination, they identified 336 proteins, collectively referred to as "TFE-dependent reversible condensate proteins (T-DRYP)"

Takekazu Kunieda, an associate professor in the Department of Biological Sciences at the University of Tokyo, said: "Although water is essential for all life we know, some tardigrades can survive for decades without water

Studies of CAHS proteins have shown that they can sense the dehydration of the cells that envelop them, forming a network of gelatinous filaments that support the shape

"Trying to understand how the CAHS protein behaves in insect and human cells is some interesting challenge," said

There are many future applications for the study of mechanisms related to the preservation of cells or biological stems

"Everything about the walking animals was charming

However, knowing how to isolate and activate these particular proteins is just the beginning

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